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For: Weigand K, Riediger C, Stremmel W, Flechtenmacher C, Encke J. Are heat stroke and physical exhaustion underestimated causes of acute hepatic failure? World J Gastroenterol 2007; 13(2): 306-309 [PMID: 17226914 DOI: 10.3748/wjg.v13.i2.306]
URL: https://www.wjgnet.com/1007-9327/full/v13/i2/306.htm
Number Citing Articles
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Vineet Rakesh, Jonathan D. Stallings, Bryan G. Helwig, Lisa R. Leon, David A. Jackson, Jaques Reifman. A 3-D mathematical model to identify organ-specific risks in rats during thermal stress. Journal of Applied Physiology 2013; 115(12) doi: 10.1152/japplphysiol.00589.2013
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Xiaoqing Ding, Binghong Gao. Heat Stress‐Mediated Multi‐Organ Injury: Pathophysiology and Treatment Strategies. Comprehensive Physiology 2025; 15(3) doi: 10.1002/cph4.70012
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Sonja Verena Schmidt, Jannik Hinzmann, Anna Stammler, Paula Wilhelms zu Bickern, Elisabete Macedo Santos, Marcus Lehnhardt, Christoph Wallner. Surviving a classic heat stroke/hyperthermia > 42 °C – a case report. International Journal of Emergency Medicine 2024; 17(1) doi: 10.1186/s12245-024-00705-2
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Elife Erarslan, ílhami Yüksel, Serap Haznedaroğ lu. Acute liver failure due to non-exertional heatstroke after sauna. Annals of Hepatology 2012; 11(1) doi: 10.1016/S1665-2681(19)31499-1
5
Jessica S. Lin, Duha Zaffar, Haris Muhammad, Peng-Sheng Ting, Tinsay Woreta, Amy Kim, Ruhail Kohli, Kiyoko Oshima, Andrew Cameron, Benjamin Philosophe, Shane Ottmann, Russell Wesson, Ahmet Gurakar. Exertional Heat Stroke-Induced Acute Liver Failure and Liver Transplantation. ACG Case Reports Journal 2022; 9(7) doi: 10.14309/crj.0000000000000820
6
Ilan S. Weisberg, Ira M. Jacobson. Cardiovascular Diseases and the Liver. Clinics in Liver Disease 2011; 15(1) doi: 10.1016/j.cld.2010.09.010
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Jie Jiao, Feihu Zhou, Hongjun Kang, Chao Liu, Mengmeng Yang, Jie Hu. Unexpected extrapyramidal symptoms and pulmonary aspergillosis in exertional heatstroke with fulminant liver failure: a case report. Journal of Medical Case Reports 2017; 11(1) doi: 10.1186/s13256-016-1184-0
8
JM Garcin, JA Bronstein, S Cremades, P Courbin, F Cointet. Acute liver failure is frequent during heat stroke. World Journal of Gastroenterology 2008; 14(1): 158-159 doi: 10.3748/wjg.14.158
9
Victoria Busto Bea, Francisco Javier García-Alonso, Víctor Moreira Vicente. Afectación hepática en el golpe de calor. Medicina Clínica 2012; 138(8) doi: 10.1016/j.medcli.2011.11.015
10
Fuquan Wang, Yan Zhang, Jianhua Li, Haifa Xia, Dingyu Zhang, Shanglong Yao. The pathogenesis and therapeutic strategies of heat stroke-induced liver injury. Critical Care 2022; 26(1) doi: 10.1186/s13054-022-04273-w
11
Youyong Tang, Chenxin Liu, Riqing Wei, Ru Li, Zhiwei Li, Keying Zhang, Xiaofeng Zhao, Qiang Ma. TRPV1/cPLA2/AA pathway contributes to ferroptosis-mediated acute liver injury in heatstroke. International Immunopharmacology 2024; 138 doi: 10.1016/j.intimp.2024.112539
12
Yukihiro Shimizu. Liver in systemic disease. World Journal of Gastroenterology 2008; 14(26): 4111-4119 doi: 10.3748/wjg.14.4111
13
Nawar S. Mohammed, Zahraa Q. Ali, Aseel Sameer Mohamed, Sazan Abdulwahab Mirza. The impact of methamphetamine on liver injury in Iraqi male addicts. Toxicology Reports 2024; 13 doi: 10.1016/j.toxrep.2024.101806
14
Renata Rodrigues Teixeira de Castro, Rubens Costa Filho, Antonio Claudio Lucas da Nóbrega. Fulminant liver failure in a street runner: Effects of heat stroke. Revista da Associação Médica Brasileira 2018; 64(3) doi: 10.1590/1806-9282.64.03.208
15
Ruff Joseph Macale Cajanding. MDMA-Associated Liver Toxicity: Pathophysiology, Management, and Current State of Knowledge. AACN Advanced Critical Care 2019; 30(3) doi: 10.4037/aacnacc2019852
16
Joanna K Moore, Eleanor Love, Darren G Craig, Peter C Hayes, Kenneth J Simpson. Acute kidney injury in acute liver failure: a review. Expert Review of Gastroenterology & Hepatology 2013; 7(8) doi: 10.1586/17474124.2013.837264
17
Philippe Ichai, Astrid Laurent-Bellue, Christophe Camus, David Moreau, Mathieu Boutonnet, Faouzi Saliba, Jean Marie Peron, Carole Ichai, Emilie Gregoire, Luc Aigle, Julien Cousty, Alice Quinart, Bertrand Pons, Marc Boudon, Stephane André, Audrey Coilly, Teresa Antonini, Catherine Guettier, Didier Samuel. Liver transplantation in patients with liver failure related to exertional heatstroke. Journal of Hepatology 2019; 70(3) doi: 10.1016/j.jhep.2018.11.024
18
Mônica Beatriz Parolin, Júlio Cezar Uili Coelho, Gustavo Rodrigues Alves Castro, Alexandre Coutinho Teixeira de Freitas. Insuficiência hepática fulminante por intermação induzida por exercício. Revista Brasileira de Medicina do Esporte 2009; 15(3) doi: 10.1590/S1517-86922009000300012
19
Shigeto Oda. Blood purification therapy for heat stroke. Nihon Shuchu Chiryo Igakukai zasshi 2008; 15(2) doi: 10.3918/jsicm.15.166
20
Donghua Du, Wenting Lv, Xiaoxia Jing, Chunwei Yu, Jiya Wuen, Surong Hasi. Camel whey protein alleviates heat stress-induced liver injury by activating the Nrf2/HO-1 signaling pathway and inhibiting HMGB1 release. Cell Stress and Chaperones 2022; 27(4) doi: 10.1007/s12192-022-01277-x
21
Sandra Coenen, Khe Tran, Jubi de Haan, Rob de Man. Liver transplantation for non-exertional heat stroke-related acute liver failure. BMJ Case Reports 2017; 2017 doi: 10.1136/bcr-2017-221029
22
Avinash Gupta, Dolly Sharma, Harshita Gupta, Ajeet Singh, Daipayan Chowdhury, Lilly Ganju, Ramesh Chand Meena. Severe heat stress modulated nuclear factor erythroid 2-related factor 2 and macrophage migration inhibitory factor pathway in rat liver. Journal of Cell Communication and Signaling 2022; 16(4) doi: 10.1007/s12079-022-00668-0
23
J. Watelet. Foie et sport. Gastroentérologie Clinique et Biologique 2008; 32(11) doi: 10.1016/j.gcb.2008.08.007
24
Sophia Görgens, Attila J. Hertelendy, Fadi Issa, David Fernandez, Ahmad Alshadad, Lindsay Davis, Jeffrey M. Franc, Janice Kung, Christina Ann Woodward, Amalia Voskanyan, Greg Ciottone. Racing in Rising Global Temperatures: A Scoping Review of Heat-related Illnesses in Endurance Running. Disaster Medicine and Public Health Preparedness 2025; 19 doi: 10.1017/dmp.2025.10135
25
Hassan Adnan Bukhari. A Systematic Review on Outcomes of Patients with Heatstroke and Heat Exhaustion. Open Access Emergency Medicine 2023;  doi: 10.2147/OAEM.S419028
26
Anaas M. Mergoum, William O. Roberts, Kong Vang, Garrett N. Manion, Brooke Echter, James D. Smith, Mark Berg. Exertional heat stroke and exercise-associated hyponatremia in collapsed endurance athletes. Sports Medicine and Health Science 2026;  doi: 10.1016/j.smhs.2026.05.005
27
Hongguang Gao, Guo Tang, Sha Yang, Ying Yang, Jie Sheng, Rong Yao, Pietro Scicchitano. Construction and Evaluation of a Predictive Model for Liver Injury Associated with Heatstroke: A Multicenter Retrospective Study. International Journal of Clinical Practice 2024; 2024(1) doi: 10.1155/2024/6485323
28
Luke A. Zabrocki, David K. Shellington, Susan L. Bratton. Pediatric Critical Care Medicine. 2014;  doi: 10.1007/978-1-4471-6362-6_49
29
Indian National Association for the Study of the Liver Consensus Statement on Acute Liver Failure (Part 1): Epidemiology, Pathogenesis, Presentation and Prognosis. Journal of Clinical and Experimental Hepatology 2020; 10(4) doi: 10.1016/j.jceh.2020.04.012
30
Michael A. Horseman, Jacquelyn Rather-Conally, Crystal Saavedra, Salim Surani. A Case of Severe Heatstroke and Review of Pathophysiology, Clinical Presentation, and Treatment. Journal of Intensive Care Medicine 2013; 28(6) doi: 10.1177/0885066611434000
31
Bertram K. Woitok, Shawki Bahmad, Gregor Lindner. A Case of Exertional Heat Stroke Complicated by Hypoxic Hepatitis. Case Reports in Emergency Medicine 2020; 2020 doi: 10.1155/2020/8724285
32
Donghua Du, Wenting Lv, Xiaoxia Jing, Xueni Ma, Jiya Wuen, Surong Hasi. Dietary supplementation of camel whey protein attenuates heat stress-induced liver injury by inhibiting NLRP3 inflammasome activation through the HMGB1/RAGE signalling pathway. Journal of Functional Foods 2021; 84 doi: 10.1016/j.jff.2021.104584
33
Donghua Du, Wenting Lv, Rina Su, Chunwei Yu, Xiaoxia Jing, Nuwenqimuge Bai, Surong Hasi. Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis. Cell Stress and Chaperones 2021; 26(2) doi: 10.1007/s12192-020-01184-z
34
Onion Gerald V. Ubaldo, Khia Quiwa, Rohana Elise Rollan, Edhel Tripon, Elizabeth Sebastian. The Fire from Within: Multiorgan Failure with Bimodal Rhabdomyolysis from Exertional Heat Stroke. Case Reports in Hepatology 2020; 2020 doi: 10.1155/2020/1305730
35
Šárka O. Southern, Jonathan D. Stallings, Danielle L. Ippolito. A systems biology approach to heat stress, heat injury, and heat stroke. Advances in Global Health through Sensing Technologies 2015 2015; 9490 doi: 10.1117/12.2183870
36
PYN Chan, KL Mok, YT Wong, PG Kan. Presentations of Runners in Kong Kong Marathon to a Local ED: A 10 Years' Glance. Hong Kong Journal of Emergency Medicine 2014; 21(4) doi: 10.1177/102490791402100401
37
Chris Bellamy, Alastair D. Burt. Macsween's Pathology of the Liver. 2018;  doi: 10.1016/B978-0-7020-6697-9.00015-7
38
Alberto Quaglia, Alastair D. Burt, Linda D. Ferrell, Bernard C. Portmann. MacSween's Pathology of the Liver. 2012;  doi: 10.1016/B978-0-7020-3398-8.00016-7
39
Min Wang, Yun Li, Yuan Cao, Meng-Meng Yang, Fu-Jing Liu, Jie Jiao, Sheng-Yuan Wang, Bin Song, Lu Wang, Yi-Qi Wu, Hong-Jun Kang. Aspartate aminotransferase-to-platelet ratio index as a novel predictor of early mortality in heat stroke patients: a multi-centre retrospective study. Annals of Medicine 2025; 57(1) doi: 10.1080/07853890.2025.2478485
40
Jiali Wang, Nanxin Li, Yunjiang Liu, Haohong Zheng, Ruihu Wu, Jingyi Zhang, Yizhou Yang, Xue Yang, Zhijun Zhong, Hualin Fu, Ziyao Zhou, Haifeng Liu, Guangneng Peng. Holstein cow milk–derived Lactobacillus plantarum L19 alleviates heat stress–induced liver injury in mice by modulating gut microbiota. Journal of Dairy Science 2026; 109(1) doi: 10.3168/jds.2025-26920
41
Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle. Physiology and Pathophysiology of Marathon Running: A narrative Review. Sports Medicine - Open 2025; 11(1) doi: 10.1186/s40798-025-00810-3
42
Ching-Wei Lee, Chin-Lin Perng, Yi-Shin Huang, Jiing-Chyuan Luo, Chi-Lai Hung, Han-Chieh Lin. Multiple Organ Failure Caused by Non-exertional Heat Stroke After Bathing in a Hot Spring. Journal of the Chinese Medical Association 2010; 73(4) doi: 10.1016/S1726-4901(10)70044-7
43
Yan Geng, Qiang Ma, Ya-Nan Liu, Na Peng, Fang-Fang Yuan, Xing-Gui Li, Ming Li, Ying-Song Wu, Bing-ling Li, Wei-bing Song, Wei Zhu, Wei-Wen Xu, Jie Fan, Lei Su. Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis. Journal of Hepatology 2015; 63(3) doi: 10.1016/j.jhep.2015.04.010
44
Chiara Mozzini, Giovanni Xotta, Ulisse Garbin, Anna Maria Fratta Pasini, Luciano Cominacini. Non-Exertional Heatstroke: A Case Report and Review of the Literature. American Journal of Case Reports 2017; 18 doi: 10.12659/AJCR.905701
45
Qian Ma, Jiaqi Dong, Xiaosong Zhang, Rong Yang, Yanming Wei. Sheng Mai San Regulating the Oxidative Stress and Mitochondrial Damage to Alleviate Liver Injury in Heat Stress Rats. Animals 2026; 16(9) doi: 10.3390/ani16091391
46
Christopher O.C. Bellamy, Alastair D. Burt. MacSween's Pathology of the Liver. 2024;  doi: 10.1016/B978-0-7020-8228-3.00015-6
47
Amanda Kuhn, Sonal Dugar, Meera Shah, Rebecca Philipsborn. Climate Change and Pediatric Gastrointestinal Health: A Narrative Review. Gastro Hep Advances 2026; 5(11) doi: 10.1016/j.gastha.2026.101116
48
Roop Gill, Timothy R. Billiar. Hepatic dysfunction after shock: Clinical parameters and biological pathways for therapeutic intervention. Journal of Organ Dysfunction 2009; 5(1) doi: 10.1080/17471060802449353
49
Kuan-Jung Chen, Tso-Hsiao Chen, Yuh-Mou Sue, Tzay-Jinn Chen, Chung-Yi Cheng. High-volume plasma exchange in a patient with acute liver failure due to non-exertional heat stroke in a sauna. Journal of Clinical Apheresis 2014; 29(5) doi: 10.1002/jca.21315
50
Laura E. Halpin, William T. Gunning, Bryan K. Yamamoto. Methamphetamine causes acute hyperthermia‐dependent liver damage. Pharmacology Research & Perspectives 2013; 1(1) doi: 10.1002/prp2.8
51
D. Karthik, J. Suresh, Y. Ravindra Reddy, G.R.K. Sharma, J.V. Ramana, G. Gangaraju, P. Pandu Ranga Reddy, Y. Pradeep Kumar Reddy, D. Yasaswini, M.J. Adegbeye, P. Ravi Kanth Reddy. Adaptive profiles of Nellore sheep with reference to farming system and season: physiological, hemato-biochemical, hormonal, oxidative-enzymatic and reproductive standpoint. Heliyon 2021; 7(5) doi: 10.1016/j.heliyon.2021.e07117
52
David W. DeGroot, Kari C. Goodwin, Gabrielle E. W. Giersch, Nisha Charkoudian. Acute kidney injury and liver damage are the most common forms of end organ damage in exertional heat illness in otherwise healthy young adults. Temperature 2026; 13(3) doi: 10.1080/23328940.2026.2680846