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For: Mansour-Ghanaei F, Taheri A, Froutan H, Ghofrani H, Nasiri-Toosi M, Bagherzadeh AH, Farahvash MJ, Mirmomen S, Ebrahimi-Dariani N, Farhangi E, Pourrasouli Z. Effect of oral naltrexone on pruritus in cholestatic patients. World J Gastroenterol 2006; 12(7): 1125-1128 [PMID: 16534857 DOI: 10.3748/wjg.v12.i7.1125]
URL: https://www.wjgnet.com/1007-9327/full/v12/i7/1125.htm
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Number Citing Articles
1
Joseph R Volpicelli, Miriam Fenton. Sustained-Release Naltrexone Formulations for the Treatment of Alcohol and Opioid Dependence. Future Neurology 2006; 1(4) doi: 10.2217/14796708.1.4.389
2
Babina Sanjel, Won-Sik Shim. Recent advances in understanding the molecular mechanisms of cholestatic pruritus: A review. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2020; 1866(12) doi: 10.1016/j.bbadis.2020.165958
3
GVMC Fernando, Nancy Preston. Refractory pruritus from malignant cholestasis: management. BMJ Supportive & Palliative Care 2023; 13(e1) doi: 10.1136/bmjspcare-2019-002051
4
Khalid M. A. Ahmed, Amro Abu Suleiman, Alaa I. Alnajdawi, Dina Abdulkader, Ahmed M. Ahmed, Ahmed R. A. Moustafa, Emma Horton. Modulation of mu-opioid pathway for the treatment of pruritus: a systematic review of 1,146 patients. Journal of Dermatological Treatment 2026; 37(1) doi: 10.1080/09546634.2026.2646801
5
Sonja Ständer, Elke Weisshaar, Thomas A. Luger. Neurophysiological and neurochemical basis of modern pruritus treatment. Experimental Dermatology 2008; 17(3) doi: 10.1111/j.1600-0625.2007.00664.x
6
Christopher Boehlke, Lisa Joos, Bettina Coune, Carola Becker, Joerg J Meerpohl, Sabine Buroh, Daniel Hercz, Guido Schwarzer, Gerhild Becker. Pharmacological interventions for pruritus in adult palliative care patients. Cochrane Database of Systematic Reviews 2024; 2024(8) doi: 10.1002/14651858.CD008320.pub4
7
Ana Marenco-Flores, Leandro Sierra, Daniela Goyes, Tamara Kahan, Vilas R. Patwardhan, Alan Bonder. Managing pruritus in chronic liver disease: An in-depth narrative review. Clinical Liver Disease 2024; 23(1) doi: 10.1097/CLD.0000000000000187
8
Nora V. Bergasa. Research in the pruritus of cholestasis: Genetics, behavioral studies, and physiomimetic interorgan models. Medical Hypotheses 2022; 166 doi: 10.1016/j.mehy.2022.110925
9
Roger W. Chapman, Kate D. Williamson. Crohn's Disease and Ulcerative Colitis. 2017;  doi: 10.1007/978-3-319-33703-6_52
10
Mariusz Sikora, Adriana Rakowska, Małgorzata Olszewska, Lidia Rudnicka. The Use of Naltrexone in Dermatology. Current Evidence and Future Directions. Current Drug Targets 2019; 20(10) doi: 10.2174/1389450120666190318121122
11
Nora V. Bergasa. Update on the Treatment of the Pruritus of Cholestasis. Clinics in Liver Disease 2008; 12(1) doi: 10.1016/j.cld.2007.11.009
12
Andreas E. Kremer, Ronald P.J. Oude Elferink, Ulrich Beuers. Pathophysiology and current management of pruritus in liver disease. Clinics and Research in Hepatology and Gastroenterology 2011; 35(2) doi: 10.1016/j.clinre.2010.10.007
13
Nora V. Bergasa. Pruritus in Primary Biliary Cirrhosis: Pathogenesis and Therapy. Clinics in Liver Disease 2008; 12(2) doi: 10.1016/j.cld.2008.02.013
14
Keith D. Lindor, Eric M. Gershwin, Raoul Poupon, Marshall Kaplan, Nora V. Bergasa, Jenny E. Heathcote. Primary biliary cirrhosis # †. Hepatology 2009; 50(1) doi: 10.1002/hep.22906
15
Shari S. Rogal, Lissi Hansen, Arpan Patel, Nneka N. Ufere, Manisha Verma, Christopher D. Woodrell, Fasiha Kanwal. AASLD Practice Guidance: Palliative care and symptom‐based management in decompensated cirrhosis. Hepatology 2022; 76(3) doi: 10.1002/hep.32378
16
Rami H. Mahmoud, Sarah G. Brooks, Gil Yosipovitch. Current and emerging drugs for the treatment of pruritus: an update of the literature. Expert Opinion on Pharmacotherapy 2024; 25(6) doi: 10.1080/14656566.2024.2349193
17
Michele Pinon, Binita M. Kamath. What's new in pediatric genetic cholestatic liver disease: advances in etiology, diagnostics and therapeutic approaches. Current Opinion in Pediatrics 2024; 36(5) doi: 10.1097/MOP.0000000000001380
18
Nora V. Bergasa. The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years. Medical Hypotheses 2018; 110 doi: 10.1016/j.mehy.2017.11.002
19
Parth Patel, Keshav Patel, Karan Pandher, Ruqiya Shama Tareen. The Role of Psychiatric, Analgesic, and Antiepileptic Medications in Chronic Pruritus. Cureus 2021;  doi: 10.7759/cureus.17260
20
Joel E. Schlosburg, Dale L. Boger, Benjamin F. Cravatt, Aron H. Lichtman. Endocannabinoid Modulation of Scratching Response in an Acute Allergenic Model: A New Prospective Neural Therapeutic Target for Pruritus. The Journal of Pharmacology and Experimental Therapeutics 2009; 329(1) doi: 10.1124/jpet.108.150136
21
Atsuki Yamamoto, Shoji Kuyama, Chiaki Kamei, Yukio Sugimoto. Characterization of scratching behavior induced by intradermal administration of morphine and fentanyl in mice. European Journal of Pharmacology 2010; 627(1-3) doi: 10.1016/j.ejphar.2009.10.066
22
Tejesh Patel, Gil Yosipovitch. Therapy of pruritus. Expert Opinion on Pharmacotherapy 2010; 11(10) doi: 10.1517/14656566.2010.484420
23
Abhishek Gairola, Aaron Wetten, Jessica Dyson. Sodium/bile acid co-transporter inhibitors currently in preclinical or early clinical development for the treatment of primary biliary cholangitis. Expert Opinion on Investigational Drugs 2024; 33(5) doi: 10.1080/13543784.2024.2343789
24
Sonja Ständer, Thomas A. Luger. Therapy of Skin Diseases. 2010;  doi: 10.1007/978-3-540-78814-0_24
25
Negar Faramarzi, Ata Abbasi, Seyed M Tavangar, Marjan Mazouchi, Ahmad R Dehpour. Opioid receptor antagonist promotes angiogenesis in bile duct ligated rats. Journal of Gastroenterology and Hepatology 2009; 24(7) doi: 10.1111/j.1440-1746.2009.05794.x
26
Society of Obstetric Medicine of Australia and New Zealand (SOMANZ) Annual Scientific Meeting Abstracts, 11–13 October 2019, Melbourne, Australia. Obstetric Medicine 2019; 12(2_suppl) doi: 10.1177/1753495X19887087
27
Andreas E. Kremer. What are new treatment concepts in systemic itch?. Experimental Dermatology 2019; 28(12) doi: 10.1111/exd.14024
28
John Halliday, Roger W. Chapman. Crohn's Disease and Ulcerative Colitis. 2012;  doi: 10.1007/978-1-4614-0998-4_47
29
Sombat Treeprasertsuk, Udomsak Silachamroon, Srivicha Krudsood, Arun Huntrup, Plengsakoon Suwannakudt, Suparp Vannaphan, Polrat Wilairatana. Ursodeoxycholic acid and artesunate in the treatment of severe falciparum malaria patients with jaundice. Journal of Gastroenterology and Hepatology 2010; 25(2) doi: 10.1111/j.1440-1746.2009.06007.x
30
Ngoc Quan Phan, Jeffrey D. Bernhard, Thomas A. Luger, Sonja Ständer. Antipruritic treatment with systemic μ-opioid receptor antagonists: A review. Journal of the American Academy of Dermatology 2010; 63(4) doi: 10.1016/j.jaad.2009.08.052
31
Aditya Kumar Bubna. Therapeutics in Dermatology - Essentials for Clinical Practice. 2025;  doi: 10.1007/978-981-95-3795-2_34
32
Miriam M. Düll, Andreas E. Kremer. Evaluation and Management of Pruritus in Primary Biliary Cholangitis. Clinics in Liver Disease 2022; 26(4) doi: 10.1016/j.cld.2022.06.009
33
Margit Baumann-Köhler, Almut Hartenstein-Pinter, Yvonne Hülsheger. Pädiatrische Palliativversorgung – Schmerzbehandlung und Symptomkontrolle. 2022;  doi: 10.1007/978-3-662-63148-5_6
34
Wiebke Pirschel, Andreas E. Kremer. Pruritus. 2016;  doi: 10.1007/978-3-319-33142-3_34
35
Andreas E. Kremer, Jamison Feramisco, Peter W. Reeh, Ulrich Beuers, Ronald P.J. Oude Elferink. Receptors, cells and circuits involved in pruritus of systemic disorders. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2014; 1842(7) doi: 10.1016/j.bbadis.2014.02.007
36
Carolyn Stull, Michael J. Lavery, Gil Yosipovitch. Advances in therapeutic strategies for the treatment of pruritus. Expert Opinion on Pharmacotherapy 2016; 17(5) doi: 10.1517/14656566.2016.1127355
37
Kimberly A. Bower, Gerit D. Mulder, Anke Reineke, Shireen V. Guide. Textbook of Interdisciplinary Pediatric Palliative Care. 2011;  doi: 10.1016/B978-1-4377-0262-0.00035-9
38
Annabel Maruani, Mahtab Samimi, Gérard Lorette. Les prurigos. La Presse Médicale 2009; 38(7-8) doi: 10.1016/j.lpm.2008.10.014
39
Andreas Binder, Jana Koroschetz, Ralf Baron. Disease mechanisms in neuropathic itch. Nature Clinical Practice Neurology 2008; 4(6) doi: 10.1038/ncpneuro0806
40
Chalermrat Bunchorntavakul, K. Rajender Reddy. Pruritus in Chronic Cholestatic Liver Disease. Clinics in Liver Disease 2012; 16(2) doi: 10.1016/j.cld.2012.03.010
41
Elliot B. Tapper, Nneka N. Ufere, Daniel Q. Huang, Rohit Loomba. Review article: current and emerging therapies for the management of cirrhosis and its complications. Alimentary Pharmacology & Therapeutics 2022; 55(9) doi: 10.1111/apt.16831
42
Juan Pablo Aristizábal Linares, Lester Andrade Almario. Eficacia de la naltrexona en el tratamiento de prurito severo. Revista Colombiana de Anestesiología 2011; 39(2) doi: 10.5554/rca.v39i2.91
43
Charles Dervout, Nicholas Boulais, Thomas Barnetche, Jean-Baptiste Nousbaum, Emilie Brenaut, Laurent Misery. Efficacy of Treatments for Cholestatic Pruritus: A Systemic Review and Meta-analysis. Acta Dermato-Venereologica 2022; 102 doi: 10.2340/actadv.v102.310
44
Kazuto Tajiri, Yukihiro Shimizu. Recent advances in the management of pruritus in chronic liver diseases. World Journal of Gastroenterology 2017; 23(19): 3418-3426 doi: 10.3748/wjg.v23.i19.3418
45
Santiago Medina Ramírez, Ana Milena Sánchez, Francisco Gómez Oquendo. Sugammadex en un paciente con insuficiencia renal crónica. Revista Colombiana de Anestesiología 2011; 39(3) doi: 10.5554/rca.v39i3.219
46
Nora V. Bergasa. Clinical Cases in Hepatology. 2022;  doi: 10.1007/978-1-4471-4715-2_15
47
Konstantin Agelopoulos, Manuel Pedro Pereira, Henning Wiegmann, Sonja Ständer. Cutaneous neuroimmune crosstalk in pruritus. Trends in Molecular Medicine 2022; 28(6) doi: 10.1016/j.molmed.2022.03.005
48
Emilie Javelle, Philippe Paule, Yves Chabrillat, Edward Lightburn, Thierry Coton, Jean-Jacques Morand. Un prurit traité par implantation d’un pacemaker. La Presse Médicale 2011; 40(9) doi: 10.1016/j.lpm.2011.03.003
49
Carola Xander, Joerg J Meerpohl, Daniel Galandi, Sabine Buroh, Guido Schwarzer, Gerd Antes, Gerhild Becker, Carola Xander. Cochrane Database of Systematic Reviews. 2013;  doi: 10.1002/14651858.CD008320.pub2
50
Nora V. Bergasa. Cirrhosis: A practical guide to management. 2015;  doi: 10.1002/9781118412640.ch26
51
Andrea A. Gossard, Keith D. Lindor. Practical Gastroenterology and Hepatology: Liver and Biliary Disease. 2010;  doi: 10.1002/9781444325249.ch10
52
Puneeta Tandon, Brian H. Rowe, Ben Vandermeer, Vincent G. Bain. The Efficacy and Safety of Bile Acid Binding Agents, Opioid Antagonists, or Rifampin in the Treatment of Cholestasis-Associated Pruritus. The American Journal of Gastroenterology 2007; 102(7) doi: 10.1111/j.1572-0241.2007.01200.x
53
Nora V. Bergasa, Deewan Deewan. Pruritus. 2010;  doi: 10.1007/978-1-84882-322-8_45
54
Hirsh D. Trivedi, Blanca Lizaola, Elliot B. Tapper, Alan Bonder. Management of Pruritus in Primary Biliary Cholangitis: A Narrative Review. The American Journal of Medicine 2017; 130(6) doi: 10.1016/j.amjmed.2017.01.037
55
Waldemar Siemens, Carola Xander, Joerg J Meerpohl, Sabine Buroh, Gerd Antes, Guido Schwarzer, Gerhild Becker. Pharmacological interventions for pruritus in adult palliative care patients. Cochrane Database of Systematic Reviews 2016; 2016(11) doi: 10.1002/14651858.CD008320.pub3
56
Juan Trivella, Binu V. John, Cynthia Levy. Primary biliary cholangitis: Epidemiology, prognosis, and treatment. Hepatology Communications 2023; 7(6) doi: 10.1097/HC9.0000000000000179
57
Kapil Vyas, Kriti Maheshwari, Praveen K. Shanmugam Reddy, Rajesh Verma, Iffat Hasan, Asit Mittal. Prescription Practices Regarding the use of Systemic Drugs in the Management of Patients with Chronic Pruritus amongst Indian Dermatologists – A Questionnaire Based Survey. Indian Dermatology Online Journal 2024; 15(1) doi: 10.4103/idoj.idoj_500_22
58
F.J. Navarro-Triviño. [Translated article] Pruritus in Dermatology: Part 2—Diseases and Their Treatment. Actas Dermo-Sifiliográficas 2023; 114(7) doi: 10.1016/j.ad.2023.06.007
59
Fatima Isa, Grace M. Turner, Geetinder Kaur, Derek Kyte, Anita Slade, Tanya Pankhurst, Larissa Kerecuk, Thomas Keeley, James Ferguson, Melanie Calvert. Patient-reported outcome measures used in patients with primary sclerosing cholangitis: a systematic review. Health and Quality of Life Outcomes 2018; 16(1) doi: 10.1186/s12955-018-0951-6
60
Nora V. Bergasa. Opiate Receptors and Antagonists. 2009;  doi: 10.1007/978-1-59745-197-0_29
61
Andreas E. Kremer, Ronald P. J. Oude-Elferink, Ulrich Beuers. Pruritus. 2010;  doi: 10.1007/978-1-84882-322-8_28
62
Jacqueline A. G. M. Langedijk, Ulrich H. Beuers, Ronald P. J. Oude Elferink. Cholestasis-Associated Pruritus and Its Pruritogens. Frontiers in Medicine 2021; 8 doi: 10.3389/fmed.2021.639674
63
Richard J. Bodnar. Endogenous opiates and behavior: 2006. Peptides 2007; 28(12) doi: 10.1016/j.peptides.2007.09.002
64
F.J. Navarro-Triviño. Prurito en dermatología. Enfermedades y su tratamiento. Parte 2. Actas Dermo-Sifiliográficas 2023; 114(7) doi: 10.1016/j.ad.2023.03.004
65
Adhyatm Bhandari, Rahul Mahajan. Skin Changes in Cirrhosis. Journal of Clinical and Experimental Hepatology 2022; 12(4) doi: 10.1016/j.jceh.2021.12.013
66
Ashley Vander Does, Cynthia Levy, Gil Yosipovitch. Cholestatic Itch: Our Current Understanding of Pathophysiology and Treatments. American Journal of Clinical Dermatology 2022; 23(5) doi: 10.1007/s40257-022-00710-2
67
Ahmad H. Ali, Elizabeth J. Carey, Keith D. Lindor. Liver Disorders. 2017;  doi: 10.1007/978-3-319-30103-7_16
68
Catherine Liu, Ashwath Elangovan, David Jerez Diaz, Lana Petrova, Anuroop Yekula, Patrick Twohig. Scratching the surface: A systematic review of modern approaches to diagnosing and treating cholestatic pruritus. World Journal of Meta-Analysis 2026; 14(3): 120937 doi: 10.13105/wjma.120937
69
Fay Louise Murray-Brown. Naltrexone for cholestatic itch: a systematic review. BMJ Supportive & Palliative Care 2021; 11(2) doi: 10.1136/bmjspcare-2020-002801
70
Elsemieke de Vries, Ruth Bolier, Jorn Goet, Albert Parés, Jef Verbeek, Marleen de Vree, Joost Drenth, Karel van Erpecum, Karin van Nieuwkerk, Frans van der Heide, Nahid Mostafavi, Jeltje Helder, Cyriel Ponsioen, Ronald Oude Elferink, Henk van Buuren, Ulrich Beuers. Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial. Gastroenterology 2021; 160(3) doi: 10.1053/j.gastro.2020.10.001
71
Vishwajit Kode, Kidist K. Yimam. Cholestatic Pruritus: Pathophysiology, Current Management Approach, and Emerging Therapies. Current Hepatology Reports 2024; 23(1) doi: 10.1007/s11901-024-00638-7
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