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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2020; 8(6): 1172-1179
Published online Mar 26, 2020. doi: 10.12998/wjcc.v8.i6.1172
Published online Mar 26, 2020. doi: 10.12998/wjcc.v8.i6.1172
Growth hormone therapy for children with KBG syndrome: A case report and review of literature
Xiu-Ying Ge, Department of Child Health, Maternal and Child Health Hospital of Linyi, Linyi 276000, Shandong Province, China
Long Ge, Department of Clinical Laboratory, Linyi People’s Hospital, Linyi 276000, Shandong Province, China
Wen-Wen Hu, Department of Pediatrics, The People's Hospital of Lanshan District, Linyi 276000, Shandong Province, China
Xiao-Ling Li, Yan-Yan Hu, Department of Pediatrics, Linyi People’s Hospital, Linyi 276000, Shandong Province, China
Author contributions: Ge XY collected the data, drafted the initial manuscript, and carried out the initial analyses; Ge L was responsible for testing the patient and her parents, and data analysis; Hu WW reviewed and revised the manuscript; Li XL performed data analyses and graphics; Hu YY conceived and designed the study, performed the final data analyses, and wrote the manuscript.
Informed consent statement: The patient’s guardian provided written informed consent to the publication of this case report.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yan-Yan Hu, MD, Attending physician, Department of Pediatrics, Linyi People’s Hospital, No. 27, East Jiefang Road, Linyi 276000, Shandong Province, China. hyanyansmile@hotmail.com
Received: November 13, 2019
Peer-review started: November 13, 2019
First decision: February 20, 2020
Revised: February 27, 2020
Accepted: March 5, 2020
Article in press: March 5, 2020
Published online: March 26, 2020
Peer-review started: November 13, 2019
First decision: February 20, 2020
Revised: February 27, 2020
Accepted: March 5, 2020
Article in press: March 5, 2020
Published online: March 26, 2020
Core Tip
Core tip: KBG syndrome is a rare autosomal dominant disorder. The percentage of height below 10th centile is relatively high at 66%. Children with KBG syndrome accompanied by short stature could benefit from growth hormone therapy.