Zhou B, Huang SS, Huang C, Liu SY. Cerebral venous sinus thrombosis in pregnancy: A case report . World J Clin Cases 2022; 10(1): 309-315 [PMID: 35071533 DOI: 10.12998/wjcc.v10.i1.309]
Corresponding Author of This Article
Shu-Yun Liu, MD, Chief Doctor, Department of Neurology, Shenzhen Longhua District Central Hospital, No. 187 Guanlan Avenue, Longhua District, Shenzhen 518000, Guangdong Province, China. liushuyun202104@163.com
Research Domain of This Article
Clinical Neurology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 7, 2022; 10(1): 309-315 Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.309
Cerebral venous sinus thrombosis in pregnancy: A case report
Biao Zhou, Shan-Shan Huang, Can Huang, Shu-Yun Liu
Biao Zhou, Can Huang, Department of Neurology, Dongguan Tungwah Hospital, Dongguan 523000, Guangdong Province, China
Shan-Shan Huang, Department of Intensive Care Unit, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518000, Guangdong Province, China
Shu-Yun Liu, Department of Neurology, Shenzhen Longhua District Central Hospital, Shenzhen 518000, Guangdong Province, China
Author contributions: Zhou B and Liu SY drafted the manuscript; Zhou B and Huang C contributed to the diagnosis and treatment of the patient; Huang SS and Liu SY revised the manuscript; all authors have read and approved the manuscript and contributed to the design of the study and interpretation of data.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Yun Liu, MD, Chief Doctor, Department of Neurology, Shenzhen Longhua District Central Hospital, No. 187 Guanlan Avenue, Longhua District, Shenzhen 518000, Guangdong Province, China. liushuyun202104@163.com
Received: July 1, 2021 Peer-review started: July 1, 2021 First decision: September 28, 2021 Revised: November 9, 2021 Accepted: November 28, 2021 Article in press: November 28, 2021 Published online: January 7, 2022
Abstract
BACKGROUND
Cerebral venous thrombosis (CVT) is a rare but life-threatening disease in pregnant women. Anticoagulation is the first-line therapy for CVT management. However, some patients have poor outcomes despite anticoagulation. Currently, the endovascular treatment of CVT in pregnant women remains controversial. We report a rare case of CVT in a pregnant woman who was successfully treated with two stent retriever devices.
CASE SUMMARY
The patient was a 29-year-old pregnant woman. She was first diagnosed with hyperemesis gravidarum due to severe nausea and vomiting for one week. As the disease progressed, she developed acute left hemiplegia. Imaging confirmed the diagnosis of superior sagittal sinus, right transverse sinus and sinus sigmoideus thrombosis. As anticoagulant therapy was ineffective, she underwent thrombectomy. After the mechanical thrombectomy, her headache diminished. Three weeks later, the patient was completely independent. At a 3-mo follow-up, no relapse of symptoms was observed.
CONCLUSION
Mechanical thrombectomy may be an effective alternative therapy for CVT in pregnant women if anticoagulation therapy fails.
Core Tip: Pregnancy-related cerebral venous thrombosis (CVT) is an uncommon and severe disease. Endovascular treatment of CVT in pregnant women remains controversial. We report a rare case of CVT in a pregnant woman who was successfully treated with two stent retriever devices. Given its rare incidence and highly diverse clinical manifestations, the clinical diagnosis of CVT is challenging. In order to avoid misdiagnosis in these high-risk patients, prompt multidisciplinary diagnosis and treatment is essential.
