Profile and determinants of unsuccessful tuberculosis outcome in rural Nigeria: Implications for tuberculosis control

Table 3 Multivariable logistic regression analysis of factors associated unsuccessful treatment outcomes among rural tuberculosis patients, Nigeria, 2011-2012

Variables	n = 1180 n (%)	Unsuccessful outcomes n (%)	Crude OR (95%CI)	Adjusted OR (95%CI)	Adjusted P-value
Total	1180	287 (24.3)
Age (yr)
≤ 40	728	168 (23.1)	1
> 40	452	119 (26.3)	1.2 (0.9-1.6)	1.3 (1.0-1.8)	0.08
Gender
Female	494	115 (23.3)	1
Male	696	172 (25.1)	1.1 (0.8-1.5)	1.2 (0.9-1.6)	0.25
Facility
Private	1035	210 (20.3)	1
Public	145	77 (53.1)	4.5 (3.1-6.4)	2.9 (1.9-4.4)	< 0.001
Type of TB
PTB smear positive	708	136 (19.2)	1
PTB smear negative	426	123 (28.9)	1.5 (1.1-1.9)	1.3 (1.0-1.8)	0.09
Extrapulmonary	46	28 (60.9)	5.3 (2.9-9.7)	2.7 (1.3-5.6)	0.009
Treatment category
New	1099	267 (24.3)	1
Retreatment	81	20 (24.7)	1.0 (0.6-1.7)	1.1 (0.6-1.9)	0.75
Regimen (n = 1099)
Regimen 1	579	157 (27.1)	1.4 (1.1-1.8)	1.3 (1.1-1.8)	0.04
Regimen 2	520	110 (21.2)
HIV status
Negative	947	196 (20.7)	1
Positive	233	91 (31.7)	2.5 (1.8-3.3)	2.1 (1.5-3.0)	< 0.001

Regimen 1: 8-mo regimen; Regimen 2: 6-mo regimen. TB: Tuberculosis; HIV: Human immunodeficiency virus.