Profile and determinants of unsuccessful tuberculosis outcome in rural Nigeria: Implications for tuberculosis control

doi:10.5662/wjm.v6.i1.118

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World Journal of Methodology

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World J Methodol. Mar 26, 2016; 6(1): 118-125
Published online Mar 26, 2016. doi: 10.5662/wjm.v6.i1.118

Table 2 Tuberculosis treatment outcomes stratified by human immunodeficiency virus status in rural Ebonyi, Nigeria, 2011-2012

Treatment outcome	Both HIV- and HIV+ n (%)	HIV-negative n (%)	HIV-positive n (%)	χ²(P value)
All TB cases				34.2 (< 0.001)
Successful	893 (75.7)	751 (79.3)	142 (60.9)
Unsuccessful	287 (24.3)	196 (20.7)	91 (39.1)
Failure	18 (1.5)	13 (1.4)	5 (2.1)	1.84 (0.18)
Death	129 (10.9)	75 (7.9)	54 (23.2)	49.0 (< 0.001)
Default	100 (8.5)	79 (8.3)	21 (9.0)	1.70 (0.19)
Transfer-out	40 (3.4)	29 (3.1)	11 (4.7)	3.76 (0.05)
Total	1180	947	233
Pulmonary TB				37.7 (< 0.001)
Successful	875 (77.2)	736 (81.0)	139 (61.8)
Unsuccessful	259 (22.8)	173 (19.0)	86 (38.2)
Failure	18 (1.6)	13 (1.4)	5 (2.2)	1.84 (0.18)
Death	121 (10.7)	69 (7.6)	52 (23.1)	50.3 (< 0.001)
Default	88 (7.8)	69 (7.6)	19 (8.4)	1.9 (0.17)
Transfer-out	32 (2.8)	22 (2.4)	10 (4.4)	5.3 (0.02)
Total	1134	909	225
Extrapulmonary TB				0.01 (0.47)¹
Successful	18 (39.1)	15 (39.5)	3 (37.5)
Unsuccessful	28 (60.9)	23 (60.5)	5 (62.5)
Failure	0	0 (0)	0 (0)	-
Death	8 (17.4)	6 (15.8)	2 (25.0)	0.25 (0.5)¹
Default	12 (26.1)	10 (26.3)	2 (25.0)	0.0 (0.68)¹
Transfer-out	8 (17.4)	7 (18.4)	1 (12.5)	0.07 (0.64)¹
Total	46	38	8
New cases				32.5 (< 0.001)
Successful	832 (75.7)	700 (79.4)	132 (60.8)
Unsuccessful	267 (24.3)	132 (20.6)	85 (39.2)
Failure	15 (1.4)	11 (1.2)	4 (1.4)	1.28 (0.26)
Death	118 (10.7)	67 (7.6)	51 (23.5)	49.7 (< 0.001)
Default	97 (8.8)	76 (8.6)	21 (9.7)	2.1 (0.15)
Transfer-out	37 (3.4)	28 (3.2)	9 (4.1)	1.86 (0.17)
Total	1099	882	217
Retreatment cases				1.8 (0.10)¹
Successful	61 (75.3)	51 (78.5)	10 (62.5)
Unsuccessful	20 (24.7)	14 (21.5)	6 (37.5)
Failure	3 (3.7)	2 (3.1)	1 (6.3)	0.58 (0.44)¹
Death	11 (13.6)	8 (12.3)	3 (18.8)	0.75 (0.31)¹
Default	3 (3.7)	3 (4.6)	0 (0)	0.58 (0.59)¹
Transfer-out	3 (3.7)	1 (1.5)	2 (12.5)	4.74 (0.08)¹
Total	81	65	16

¹Fisher’s exact P-value was reported; TB: Tuberculosis; HIV: Human immunodeficiency virus; HIV+: HIV-positive; HIV-: HIV-negative.

Citation: Ukwaja KN, Oshi SN, Alobu I, Oshi DC. Profile and determinants of unsuccessful tuberculosis outcome in rural Nigeria: Implications for tuberculosis control. World J Methodol 2016; 6(1): 118-125
URL: https://www.wjgnet.com/2222-0682/full/v6/i1/118.htm
DOI: https://dx.doi.org/10.5662/wjm.v6.i1.118