Possible roles of short-chain fatty acids in the pathophysiology and treatment of irritable bowel syndrome

Figure 3 The content of propionic acid in feces. A: Fecal propionic acid level in irritable bowel syndrome patients who received 60 g of the donor’s feces; B: Correlation of the irritable bowel syndrome severity scoring system total score with the fecal propionic acid level. ^aP < 0.05; ^bP < 0.01 compared with the baseline values. Based on data from El-Salhy et al[32-34]. FMT: Fecal microbiota transplantation; IBS-SSS: Irritable bowel syndrome-severity scoring system.