Possible roles of short-chain fatty acids in the pathophysiology and treatment of irritable bowel syndrome

Figure 2 Fecal acetic acid content. A: Fecal acetic acid level in irritable bowel syndrome patients who received 60 g of the donor’s feces; B: Correlation of the fecal acetic acid level with the irritable bowel syndrome-severity scoring system total score. ^aP < 0.05; ^bP < 0.01 compared with the baseline values. Based on pooled data from El-Salhy et al[32-34]. FMT: Fecal microbiota transplantation; IBS-SSS: Irritable bowel syndrome-severity scoring system.