Possible roles of short-chain fatty acids in the pathophysiology and treatment of irritable bowel syndrome

Figure 1 Post-fecal microbiota transplantation changes in irritable bowel syndrome patients receiving 60 g of donor feces. A: Total fecal short chain fatty acids levels; B: Fecal butyric acid level. ^aP < 0.05, ^bP < 0.0001, ^cP < 0.01 vs the baseline values. Based on pooled data from El-Salhy et al[32-34]. The total fecal short chain fatty acids, acetic acid, propionic acid, and butyric acid levels in the cited references were analyzed using gas chromatography (Agilent 7890A, Agilent, CA, United States). SCFA: Short chain fatty acids; FMT: Fecal microbiota transplantation.