Trends of characteristics and outcomes of donors and recipients of deceased donor liver transplantation in the United States: 1990 to 2013

Table 8 Cox proportional hazards regression of survival after liver transplantation

	Unadjusted HR (95%CI)	Adjusted HR (95%CI)1
Over all patient survival
Period 2 (1995-1999 vs 1990-1994)	0.90 (0.87-0.93)	0.90 (0.84-0.94)
Period 3 (2000-2004 vs 1990-1994)	0.87 (0.84-0.90)	0.76 (0.72-0.81)
Period 4 (2005-2009 vs 1990-1994)	0.83 (0.80-0.86)	0.67 (0.62-0.72)
5 yr patient survival
Period 2 (1995-1999 vs 1990-1994)	0.90 (0.86-0.95)	0.90 (0.82-0.98)
Period 3 (2000-2004 vs 1990-1994)	0.90 (0.86-0.95)	0.80 (0.73-0.88)
Period 4 (2005-2009 vs 1990-1994)	0.86 (0.82-0.90)	0.73 (0.66-0.80)
Over all graft survival
Period 2 (1995-1999 vs 1990-1994)	0.90 (0.87-0.93)	0.88 (0.83-0.93)
Period 3 (2000-2004 vs 1990-1994)	0.84 (0.82-0.87)	0.74 (0.70-0.79)
Period 4 (2005-2009 vs 1990-1994)	0.80 (0.76-0.81)	0.66 (0.62-0.71)
5 yr graft survival
Period 2 (1995-1999 vs 1990-1994)	0.91 (0.87-0.95)	0.89 (0.82-0.96)
Period 3 (2000-2004 vs 1990-1994)	0.87 (0.84-0.91)	0.77 (0.71-0.84)
Period 4 (2005-2009 vs 1990-1994)	0.81 (0.76-0.84)	0.71 (0.65-0.77)

¹Adjusted for donor age, gender, BMI, ethnicity, cause of death and recipient’s age, gender, BMI, ethnicity, CIT, cause of liver failure, waitlist time, diabetes, COPD, HTN, dialysis, angina, functional status, medical condition. HR: Hazard ratio; CI: Confidence interval; CIT: Cold ischemia time; BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; HTN: Hypertension.