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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jan 9, 2023; 12(1): 35-40
Published online Jan 9, 2023. doi: 10.5492/wjccm.v12.i1.35
Published online Jan 9, 2023. doi: 10.5492/wjccm.v12.i1.35
Vasopressin-induced hyponatremia in an adult normotensive trauma patient: A case report
Maulik K Lathiya, Emily Pepperl, Susan M Cullinan, Department of Emergency Medicine, Mayo Clinic Health System, Eau Claire, WI 54703, United States
Daniel Schaefer, Hussam Al-Sharif, Adel Zurob, Antonios Charokopos, Department of Pulmonary and Critical Care Medicine, Mayo Clinic Health System, Eau Claire, WI 54703, United States
Author contributions: Lathiya MK, Schaefer D, Cullinan SM and Charokopos A designed and conceptualized the research; Lathiya MK and Pepperl E performed the research; Lathiya MK, Al-Sharif H, Zurob A, Cullinan SM and Charokopos A wrote the paper and assisted with graphics; Lathiya MK and Charokopos A revised the paper.
Informed consent statement: Informed written consent was obtained from the patient.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: All authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Antonios Charokopos, MD, Department of Pulmonary and Critical Care Medicine, Mayo Clinic Health System, 1221 Whipple Street, Eau Claire, WI 54703, United States. charokopos.antonios@mayo.edu
Received: September 24, 2022
Peer-review started: September 24, 2022
First decision: October 21, 2022
Revised: November 3, 2022
Accepted: November 23, 2022
Article in press: November 23, 2022
Published online: January 9, 2023
Peer-review started: September 24, 2022
First decision: October 21, 2022
Revised: November 3, 2022
Accepted: November 23, 2022
Article in press: November 23, 2022
Published online: January 9, 2023
Core Tip
Core Tip: While hyponatremia can have many causes, vasopressin-induced hyponatremia in normotensive patients is unusual. Since the coronavirus disease 2019 pandemic, vasopressin use has increased in intensive care units across the country, and vasopressin-induced hyponatremia is likely underrated. We have intervened by discontinuing vasopressin, which led to rapid overcorrection of the sodium, and thus required temporary exogenous desmopressin and a dextrose 5% in water infusion. Through his care, the patient's serum sodium returned to normal and he made a full recovery. This makes our case unique.