Gastroesophageal reflux disease in pediatric esophageal atresia: Assessment of clinical symptoms and pH-impedance data

Table 3 pH-impedance data of esophageal atresia patients

pH-impedance parameter	EA without GERD	EA with GERD	P value
AET (%)	2.59, 95%CI: 1.68 to 3.5	11.62, 95%CI: 7.54 to 15.7, P = 0.0066	< 0.001
Number of RBM	40.3, 95%CI: 34.3 to 46.3	67.3, 95%CI: 55.27 to 79.32	< 0.005
Longest acid exposure in min	9.37, 95%CI: 5.26 to 13.5, P = 0.0104	46.8, 95%CI: 28.39 to 65.26, P = 0.0061	< 0.001
Proximal events	6.59, 95%CI: 3.1 to 10.1, P = 0.0249	10.95, 95%CI: 6.24 to 15.56, P = 0.0089	0.151
Index of proximal events1	0.17, 95%CI: 0.09 to 0.27, P = 0.0052	0.16, 95%CI: 0.1 to 0.22	0.939
Distal MNBI in kOhm	1.99, 95%CI: 1.72 to 2.26	1.44, 95%CI: 1.21 to 1.67	< 0.005
SAP (> 95%/< 95%)	8/17	3/20	0.03

¹In 4 cases in the group of EA without GERD, proximal events were not registered. Data are presented as mean with 95%CI by Shapiro-Wilk test. EA: Esophageal atresia; GERD: Gastroesophageal reflux disease; CI: Confidence interval; AET: Acid exposure time; MNBI: Mean nocturnal baseline impedance; RBM: Retrograde bolus movements.