Outcomes and adverse events following intra-arterial chemotherapy for retinoblastoma: A single center study in South India

Table 1 Intra-arterial chemotherapy in retinoblastoma as primary or secondary treatment in 17 eyes

	Primary IAC (n = 9)	Secondary IAC with intravitreal chemotherapy (n = 8)	P value (effect size)	95%CI
Median age at presentation months	14 (6, 48)	18 (2, 36)	0.73 (0.09)	0.13-1.30
Sex
Male	2 (22)	3 (38)	0.49 (0.17)	-2.80 to 3.80
Female	7 (78)	5 (62)
Study eye
Oculus dexter	3 (33)	5 (62)	0.23 (0.29)	-3.90 to 6.80
Oculus sinister	6 (67)	3 (38)
Laterality
Unilateral	8 (89)	3 (38)	0.03 (0.54)	-2.80 to 12.60
Bilateral	1 (11)	5 (62)
Inheritance
Hereditary	1 (11)	5 (63)	0.03 (0.54)	-1.80 to 11.60
Sporadic	8 (89)	3 (37)

Data was presented as n (%). For categorical variables, χ² test or Fisher’s exact test was used to test the association between the variables. For continuous variables, the Mann-Whitney U test (non-parametric equivalent of independent sample t test) was used to test the significance between the median of the two groups. IAC: Intra-arterial chemotherapy; CI: Confidence interval.