Incidence of gastro-esophageal reflux disease in mechanically ventilated full-term Egyptian neonates by detection of pepsin in endotracheal aspirate

Table 5 Relation of pepsin detection in sample B with pepsin levels and pepsin detection in sample A and sample C of the studied cases, n (%)

	Pepsin detection in sample B		Test value	P value
	No detection (n = 18)	Detected (n = 78)
Sample A ETA pepsin (ng/mL)			-1.314	0.189
					Median (IQR)
0.48 (0.02–1.9)	0.94 (0.28–2.67)
Range	0.01–7.27	0.01–31
Pepsin detection in sample A			3.752	0.053
					No detection
7 (38.9)	14 (17.9)
Detected	11 (61.1)	64 (82.1)
Sample C ETA pepsin (ng/mL)			-1.794	0.073
					Median (IQR)
0.03 (0.01–1.43)	0.51 (0.06–1.73)
Range	0.01–4.02	0.01–8.68
Pepsin detection in sample C			4.494	0.034a
					No detection
7 (58.3)	15 (26.8)
Detected	5 (41.7)	41 (73.2)

^aP < 0.05.

ETA: Endotracheal aspirate; IQR: Interquartile range.