Incidence of gastro-esophageal reflux disease in mechanically ventilated full-term Egyptian neonates by detection of pepsin in endotracheal aspirate

Table 3 Relation of pepsin detection in sample A, B, and C with endotracheal aspirate culture of the studied cases, n (%)

		Pepsin detection in sample A		Test value	P value
		No detection (n = 21)	Detected (n = 76)
ETA culture	Not done	5 (23.8)	8 (10.5)	4.0961	0.129
	No growth	10 (47.6)	30 (39.5)
	Positive	6 (28.6)	38 (50)
Pepsin detection in sample B
ETA culture	Not done	2 (11.1)	11 (14.1)	1.0391	0.595
	No growth	6 (33.3)	34 (43.6)
	Positive	10 (55.6)	33 (42.3)
Pepsin detection in sample C
ETA culture	Not done	3 (13.6)	4 (8.5)	0.506	0.776
	No growth	9 (40.9)	22 (46.8)
	Positive	10 (45.5)	21 (44.7)

¹χ² test, lower limit of pepsin detection is 0.0625 ng/mL.

ETA: Endotracheal aspirate.