Observational Study
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World J Clin Pediatr. Aug 8, 2014; 3(3): 59-68
Published online Aug 8, 2014. doi: 10.5409/wjcp.v3.i3.59
Recurrent headaches may be caused by cerebral toxoplasmosis
Joseph Prandota, Anna Gryglas, Aleksander Fuglewicz, Agata Żesławska-Faleńczyk, Barbara Ujma-Czapska, Leszek Szenborn, Janusz Mierzwa
Joseph Prandota, Anna Gryglas, Aleksander Fuglewicz, Agata Żesławska-Faleńczyk, Department of Social Pediatrics, Faculty of Health Sciences, Wroclaw Medical University, 51618 Wroclaw, Poland
Barbara Ujma-Czapska, Department of Pediatric Neurology, Taddeus Marciniak Specialistic Hospital, 50420 Wroclaw, Poland
Leszek Szenborn, Department of Pediatrics and Infectious Diseases, Wroclaw Medical University, 50345 Wroclaw, Poland
Janusz Mierzwa, Department of Neurosurgery, Wroclaw Medical University, 50420 Wroclaw, Poland
Author contributions: Prandota J, Gryglas A, Fuglewicz A, Żesławska-Faleńczyk A, Ujma-Czapska B, Szenborn L and Mierzwa J equally contributed to this paper.
Correspondence to: Joseph Prandota, MD, PhD, Professor, Department of Social Pediatrics, Faculty of Health Sciences, Wroclaw Medical University, 5 Bartla Str., 51618 Wroclaw, Poland. jozef.prandota@am.wroc.pl
Telephone: +48-71-3484210 Fax: +48-71-3432086
Received: October 16, 2013
Revised: March 21, 2014
Accepted: April 25, 2014
Published online: August 8, 2014
Core Tip

Core tip: This work estimated the seroprevalence and characteristics of Toxoplasma gondii (TG) infection in 178 children admitted consecutively to the Pediatric Neurology Department because of recurrent headaches. Nineteen children had significantly increased serum anti-TG IgG antibody levels and high avidity index which indicated chronic infection. It is suggested to treat these patients specifically for 5-7 d and eventually be aware of the Jarisch-Herxheimer reaction.