Hepatoma-derived growth factor expression as a prognostic marker in cervical cancer

Table 2 Univariate analysis of overall survival with clinicopathological factors in uterine cervical cancer patients

Factor	Category	No. of patientsn = 88	No. of deathsn = 14	5-yroverall survival rate	P value
Age (yr)	1: ≤ 50	37	4	89%	0.27
	2: > 50	51	10	79%
Histological differentiation	1: Keratinized SQ	29	5	81%	0.04a
	2: Nonkeratinized SQ	58	8	85%
	3: Adenosquamous carcinoma	1	1	0%
Lymphatic permeation	1: Absent	53	6	88%	0.15
	2: Present	35	8	75%
Vascular permeation	1: Absent	65	6	90%	0.005
	2: Present	23	8	63%
Depth of invasion (pT)	1: T1	41	1	97%	0.001b
	2: T2	43	10	75%	0.0001d
	3: T3	3	2	0%
	4: T4	1	1	0%
Lymph node metastasis (pN)	1: Absent	64	2	97%	0.0001
	2: Present	24	12	49%
Stage	1: I	43	2	95%	0.0001d
	2: II	36	4	88%
	3: III	5	4	20%
	4: IV	4	4	0%
Hepatoma-derived growth factor expression	1: Level 0	19	0	100%	0.0036a
	2: Level 1	11	0	100%
	3: Level 2	58	14	74%

^aP: 1 and 2 vs 3;

^bP: 1 vs 2-4;

^dP: 1 and 2 vs 3 and 4. SQ: Squamous cell carcinoma.