Observational Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Hematol. Aug 6, 2014; 3(3): 105-114
Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.105
Table 2 Multivariate analysis of prognostic factors affecting survival in non-acute promyelocytic leukemia patient
Risk factors
Chromosomal abnormalityNCCN
SWOG
CALGB
HR (95%CI) PHR (95%CI) PHR (95%CI) P
Age in years0.0310.0430.026
≤ 64111
65-741.33 (1.06-1.58)1.39 (1.13-1.64)1.40 (1.15-1.66)
≥ 751.88 (1.59-2.04)1.82 (1.60-2.05)1.91 (1.67-2.13)
Performance status0.0120.0280.019
0-2111
3-41.94 (1.15-3.26)1.80 (1.06-3.05)1.88 (1.11-3.20)
Intensity of induction therapy0.0410.0290.027
Intensive, less-intensive111
Best supportive care1.74 (2.02-2.96)1.80 (1.06-3.07)1.83 (1.07-3.14)
Antecedent hematological disease0.0070.0070.004
No111
Yes1.92 (1.20-3.08)1.90 (1.19-3.05)2.03 (1.25-3.27)
Chromosomal abnormality0.001< 0.001< 0.001
Favorable, intermediate111
Unfavorable1.98 (1.31-2.99)1.44 (0.55-3.78)1.56 (0.63-3.87)