Effect of non-steroidal anti-inflammatory drugs on fracture healing in children: A systematic review

Table 2 Evidence table

Study	Ref.	Level of evidence
Risk factors for nonunion of bone fracture in pediatric patients: An inception cohort study of 237033 fractures	Zura et al[30], 2018	Level II
Perioperative ketorolac use in children undergoing lower extremity osteotomies	Kay et al[31], 2010	Level III
Complications of ketorolac use in children undergoing operative fracture care	Kay et al[32], 2011	Level III
Does the use of ibuprofen in Children with extremity fractures increase their risk for bone healing complications?	DePeter et al[33], 2017	Level I
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain	Drendel et al[34], 2009	Level I
Effect of NSAID use on bone healing in pediatric fractures: A preliminary, prospective, randomized, blinded study	Nuelle et al[35], 2020	Level I

NSAIDs: Non-steroidal anti-inflammatory drugs.