Paraneoplastic syndromes associated with lung cancer

Table 1 Criteria for the diagnosis of paraneoplastic endocrine syndromes

Abnormal endocrine function without physiologic feedback regulation

The absence of metastasis in the respective endocrine gland

Deterioration with increasing tumor burden

Improvement in endocrine function with the treatment of the tumor

Evidence of the presence of hormones in the tumor or hormone synthesis by the tumor