Pattarajierapan S, Sukphol N, Junmitsakul K, Khomvilai S. Oncologic safety of colonic stenting as a bridge to surgery in left-sided malignant colonic obstruction: Current evidence and prospects. World J Clin Oncol 2022; 13(12): 943-956 [PMID: 36618077 DOI: 10.5306/wjco.v13.i12.943]
Corresponding Author of This Article
Sukit Pattarajierapan, MD, Doctor, Surgeon, Surgical Endoscopy Colorectal Division, Department of Surgery, Faculty of Medicine, Chulalongkorn University, 1873 Rama IV Road, Pathumwan, Bangkok 10330, Thailand. sukit.p@chulahospital.org
Research Domain of This Article
Oncology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Sukit Pattarajierapan, Nattapanee Sukphol, Karuna Junmitsakul, Supakij Khomvilai, Surgical Endoscopy Colorectal Division, Department of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
Author contributions: Pattarajierapan S wrote the article; Sukphol N, Junmitsakul K, and Khomvilai S made substantial contributions to the content, offered critical revisions, and approved the final version of the article.
Conflict-of-interest statement: Dr. Sukit Pattarajierapan, Nattapanee Sukphol, Karuna Junmitsakul and Supakij Khomvilai have no conflicts of interest or financial ties to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sukit Pattarajierapan, MD, Doctor, Surgeon, Surgical Endoscopy Colorectal Division, Department of Surgery, Faculty of Medicine, Chulalongkorn University, 1873 Rama IV Road, Pathumwan, Bangkok 10330, Thailand. sukit.p@chulahospital.org
Received: September 2, 2022 Peer-review started: September 2, 2022 First decision: September 27, 2022 Revised: October 10, 2022 Accepted: December 8, 2022 Article in press: December 8, 2022 Published online: December 24, 2022
Core Tip
Core Tip: Although the concept of self-expandable metal stent (SEMS) insertion as a bridge to surgery in patients with left-sided malignant colonic obstruction is promising, there remain concerns of adverse oncologic outcomes. Nowadays, three possible mechanisms of tumor dissemination from SEMS have been proposed: (1) SEMS-related perforation; (2) increased circulating tumor cells; and (3) aggressive pathological features after SEMS placement. However, among these, only SEMS-related perforation clearly influences adverse oncologic outcomes. The other two mechanisms lack consistent clinical evidence for their association with decreased survival. Therefore, further collaborating studies are needed to validate the clinical impact of these hypotheses.
