Eosinophilic gastroenteritis: Approach to diagnosis and management

Table 4 Published cases of eosinophilic gastroenteritis treated with cromolyn sodium

Ref.	Patient no.	Intestinal layer	Location	Previous treatment	Response
Moots et al[71], 1988	1	Mucosal +/- muscular	Small intestine + colon	Prednisone, cyclophosphamide	Response (+) in 10 wk Maintenance over 2.5 yr
Talley et al[4], 1990	3	Mucosal	-	None	1 → Response (+) 2 → No response
Di Gioacchino et al[72], 1990	2	Mucosal	Stomach + duodenum	None	Clinical and histologic response (+) after 4-5 mo
Beishuizen et al[73], 1993	2	Mucosal	Upper gastrointestinal tract	Steroids	Prolonged response (+)
Van Dellen et al[74], 1994	1	Mucosal	Stomach + duodenum	Elemental diet (poorly tolerated)	Response (+)
Russel et al[52], 1994	1	Mucosal	Ileum + colon	Steroid dependent	None (failure to taper steroids)
Pérez-Millán et al[75], 1997	1	Serosal	Duodenum	None	Response (+) over 6 mo
Suzuki et al[76], 2003	1	Mucosal	Stomach + duodenum	Targeted elimination diet (poorly tolerated)	Response (+) (in combination with ketotifene)
Sheikh et al[77], 2009	3	Mucosal Mucosal Mucosal +/- muscular	Esophagus + stomach + duodenum Stomach + duodenum + colon Esophagus + stomach + duodenum + colon	Steroid refractory None Steroid dependent	Not effective Partial response Response (+) with tapering of prednisone over 6 mo