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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Nov 6, 2016; 7(4): 513-523
Published online Nov 6, 2016. doi: 10.4292/wjgpt.v7.i4.513
Published online Nov 6, 2016. doi: 10.4292/wjgpt.v7.i4.513
Eosinophilic gastroenteritis: Approach to diagnosis and management
Antoine Abou Rached, Weam El Hajj, Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Lebanese University, Hadath, Beirut 2903 1308, Lebanon
Author contributions: Abou Rached A and El Hajj W conceived and designed the study; El Hajj W performed the literature review and drafted the article; Abou Rached A critically revised the article for intellectual content and gave final approval of the manuscript.
Conflict-of-interest statement: Neither author has any personal or financial interests related to the publication of this study or its findings.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Antoine Abou Rached, MD, MBAIP, Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Lebanese University, Hadath, Campus, PO Box #3, Hadath, Beirut 2903 1308, Lebanon. abourachedantoine@gmail.com
Telephone: +961-5-451100 Fax: +961-5-455131
Received: December 5, 2015
Peer-review started: December 7, 2015
First decision: February 15, 2016
Revised: July 23, 2016
Accepted: August 15, 2016
Article in press: August 17, 2016
Published online: November 6, 2016
Peer-review started: December 7, 2015
First decision: February 15, 2016
Revised: July 23, 2016
Accepted: August 15, 2016
Article in press: August 17, 2016
Published online: November 6, 2016
Core Tip
Core tip: Eosinophilic gastroenteritis (EGE) is a heterogeneous inflammatory bowel disorder, which commonly follows a chronic and relapsing course. To date, only single cases or small case series provide insights into its diagnosis and management. This manuscript reviews the different diagnostic tools utilized in practice and provides an algorithm for diagnosis. It also provides a summary of the therapeutic modalities applied in EGE management, which are placed within the context of an algorithm for systematic application of the different strategies according to the initial disease severity.