Eosinophilic gastroenteritis: Approach to diagnosis and management

Table 1 Eosinophilic gastroenteritis severity upon presentation

Initial findings	Mild	Moderate	Severe	Complicated
Clinical
Abdominal pain	Mild	Moderate	Severe
Vomiting	Mild (< 3/d)	Moderate (3-7/d)	protracted (> 8/d)
Diarrhea	< 6 BM/d	6-12 BM/d	> 12 BM/d
Weight loss1[35]	Non-significant	1 wk 1%-2% 1 mo 5% 3 mo 7.5% 6 mo 10%	1 wk > 2% 1 mo > 5% 3 mo > 7.5% 6 mo > 10%
Laboratory
Alb, g/dL	> 3	2.5-3	< 2.5
HB, g/dL[36]	9.5-11	8-9.5	< 8
AEC, cells/μL[37]	< 1500	1500-5000	> 5000
Radiologic
Ascites	None or mild	Moderate volume	Large volume	Perforation
Intestinal wall thickening[38]	Mild (1-2 cm) Focal (< 10 cm)	Marked (> 2 cm), segmental (10-30 cm)	Sub-occlusion, extensive (> 30 cm)	Occlusion Intussusception
Endoscopy
Mucosal inflammation[39]	Normal or mild erythema	Moderate	Severe with pseudo-polyps/bleeding	GOO Pyloric stenosis
Histology
Structural damage2[34]	Minimal	Moderate	Severe

¹Percent weight change = [(usual weight - actual weight)/(usual weight)] × 100

²Subjective assessment by expert pathologist. AEC: Absolute eosinophilic count; Alb: Albumin; GOO: Gastric outlet obstruction; HB: Hemoglobin.