Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome

Table 1 Baseline characteristics of the patient population stratified according to response to endotherapy

Parameters	Total (n = 41)	Complete response (n = 20)	Partial response (n = 14)	No response (n = 7)
Recipient mean age (year ± SD)	40.02 ± 15.45	37.5 ± 17.03	41.0 ± 14.3	45.29 ± 13.15
Donor mean age (year ± SD)	39.9 ± 8.9	38.5 ± 6.85	39.86 ± 11.2	44.0 ± 9.03
Recipient gender - male, n (%)	36 (87.8)	16 (80)	14 (100)	6 (85.7)
Donor gender - male, n (%)	9 (22)	4 (20)	4 (28.5)	1 (14.2)
Transplant setting, n (%)
CLD	32 (78)	14 (70)	12 (85.7)	6 (85.7)
ALF	9 (22)	6 (30)	2 (14.3)	1 (14.3)
Etiology of CLD (n = 32)
Alcohol	12 (37.5)	4 (33.3)	6 (50)	2 (16.7)
Cryptogenic	13 (40.6)	6 (46.1)	5 (38.4)	2 (15.5)
Others (Wilsons, hepatitis B, hepatitis C, autoimmune)	7 (21.8)	3 (42.8)	2 (28.6)	2 (28.6)
MELD	23.45 ± 6.4	25.07 ± 7.2	22.46 ± 4.75	21.83 ± 6.52
Intra-operative variables
Cold Ischemia time (secs) (mean ±)	51.5 ± 29.2	53.3 ± 34.4	54.08 ± 25.6	43.57 ± 28.4
Blood transfusions (mean ±)	4.1 ± 2.8	4.3 ± 2.3	4.3 ± 3.5	3.2 ± 2.2
Post op complications
Hepatic artery thrombosis, n (%)	5 (12.2)	0 (0)	3 (60)	2 (40)
Bile leak	26 (65)	12 (60)	10 (71.4)	4 (57.1)
Mean interval between LT and leak (d)	18.4	20.85	12.6	5.6
Persistent bile leak > 4 wk, n (%)	14 (34.1)	2 (14.2)	8 (57.1)	4 (28.7)
Clinical presentation, n (%)
Cholangitis	15 (36.6)	6 (30)	7 (42.1)	2 (13.4)
Pruritus alone	16 (39)	7 (43.75)	4 (25)	5 (31.25)
Jaundice	16 (39)	5 (31.25)	6 (37.5)	5 (31.25)

CLD: Chronic liver disease; ALF: Acute liver failure; MELD: Model for end-stage liver disease.