Iron deficiency anemia in inflammatory bowel disease

Table 2 Laboratory findings in iron deficiency anemia, anemia of chronic disease, mixed iron deficiency anem and anemia of chronic disease[16,31]

Laboratory measures	IDA	ACD	IDA and ACD
Serum iron	↓	↓	↓
Hemoglobin	↓	↓	↓
MCV	↓	↓ or normal	↓ or normal
CRP	Normal	↑↑	↑
Serum ferritin	↓	↑	↑ or normal
Transferrin	↑	↓ or normal	↓
Transferrin saturation	↓	↓	↓
sTfR	↑	↓	↑ or normal
sTfR- Ferritin index	High (> 2)	Low (< 1)	High (> 2)
Reticulocyte Hb content (CHr, pg)	< 28	≥ 28	< 28
Zinc protoporphyrin (μmol/mol heme)	> 40	< 40	> 40
Percentage of hypochromic RBC	> 5	< 5	> 5
Hepcidin	↓	↑	↑

↓: Low/decreases; ↑: High/increases; ↑↑: Very high; IDA: Iron deficiency anemia; ACD: Anemia of chronic disease; MCV: Mean corpuscular volume; CRP: C-reactive protein; sTfR: Soluble transferrin receptor; Hb: Hemoglobin; RBC: Red blood cell.