Value of dual energy computed tomography with material decomposition algorithm in assessing intestinal creeping fat in Crohn’s disease

doi:10.4329/wjr.122056

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Radiol. Jun 28, 2026; 18(6): 122056
Published online Jun 28, 2026. doi: 10.4329/wjr.122056

Table 5 Relationship of Crohn’s disease intestinal creeping fat with intestinal tumor necrosis factor-α and transforming growth factor-β protein expression, mean ± SD

Group	Intestinal CrF	TNF-α (ng/L)	TGF-β
Normal control (n = 30)	17.24 ± 5.16	0.002 ± 0.001	0.003 ± 0.001
Active phase (n = 30)	104.67 ± 26.51^a	0.047 ± 0.001^a	0.011 ± 0.002^a
Quiescent phase (n = 30)	32.69 ± 11.42^a^,^b	0.009 ± 0.002^a^,^b	0.005 ± 0.002^a^,^b

^aP < 0.05 vs the normal control group.

^bP < 0.05 vs the active Crohn’s disease group.

r = 0.936 for intestinal tumor necrosis factor-α expression; r = 0.891 for intestinal transforming growth factor-β protein expression. CrF: Creeping fat; CD: Crohn’s disease; TNF-α: Tumor necrosis factor-α; TGF: Transforming growth factor-β.

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Citation: Dong LW, Chen HJ, Chen CC, Lan C. Value of dual energy computed tomography with material decomposition algorithm in assessing intestinal creeping fat in Crohn’s disease. World J Radiol 2026; 18(6): 122056
URL: https://www.wjgnet.com/1949-8470/full/v18/i6/122056.htm
DOI: https://dx.doi.org/10.4329/wjr.122056

Dong LW, Chen HJ, Chen CC, Lan C. Value of dual energy computed tomography with material decomposition algorithm in assessing intestinal creeping fat in Crohn’s disease. World J Radiol 2026; 18(6): 122056 [PMID: 42395102 DOI: 10.4329/wjr.122056]

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