Magnetic resonance imaging-based radiomics signature for predicting preoperative staging of esophageal cancer

Figure 1 Flowchart of the study. A: Original magnetic resonance imaging images, including T2-weighted imaging (T2WI) and T1-weighted imaging (T1WI)-Gd; B: Segmentation of both T2WI and T1WI-Gd images delineated the tumor region; C: Radiomic features were extracted from the tumor region, including shape, first-order histogram, texture and wavelet group analysis; D: A series of features were selected to build the radiomics signature using the minimal redundancy maximal relevance and the least absolute shrinkage and selection operator method; E: The classification performance of the radiomic signature was evaluated using the receiver operating characteristic curves in both the primary and validation cohort. ROC: Receiver operating characteristic; T1WI: T1-weighted imaging; T2WI: T2-weighted imaging.