Primary esophageal lymphoma in immunocompetent patients: Two case reports and literature review

Figure 1 Barium esophagogram shows irregular outline and multiple filling defects (arrow), with short segment narrowing of the distal segment of the esophagus involving right side posterolaterally.

Figure 2 Computed tomography scan of the thorax. A: Plain computed tomography (CT) showing asymmetrical thickening of the esophageal wall (white arrow) with maintenance of the surrounding fat plane. No mediastinal lymphadenopathy is seen; B: Contrast-enhanced CT shows moderate enhancement of the lesion (white arrow); C: Coronal multiplanar reconstructed (MPR) CT image demonstrating the thickened esophagus (white arrow); D: Sagittal MPR CT image showing extension of the lesion (between two arrows).

Figure 3 Photomicrograph of the biopsy specimen demonstrating large transformed lymphoid cells with vesicular nuclei and prominent nucleoli, which was suggestive of diffuse large B-cell lymphoma (hematoxylin and eosin, × 200).

Figure 4 Esophagogastroduodenoscopy (A and B) showing multiple solid, firm nodular lesions in the lower esophagus. Overlying mucosa appearing relatively normal (black arrows).