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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Evaluating pediatric ureteropelvic junction obstruction: Dynamic magnetic resonance urography vs renal scintigraphy 99m-technetium mercaptoacetyltriglycine
Yousuf Al-Shaqsi, Matthieu Peycelon, Annabel Paye-Jaouen, Elisabeth Carricaburu, Anca Tanase, Christine Grapin-Dagorno, Alaa El-Ghoneimi
Yousuf Al-Shaqsi, Department of Pediatric Surgery, Sultan Qaboos University Hospital, Muscat 123, Oman
Yousuf Al-Shaqsi, Matthieu Peycelon, Annabel Paye-Jaouen, Elisabeth Carricaburu, Christine Grapin-Dagorno, Alaa El-Ghoneimi, Service de Chirurgie Viscérale et Urologie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France
Yousuf Al-Shaqsi, Matthieu Peycelon, Annabel Paye-Jaouen, Anca Tanase, Alaa El-Ghoneimi, Centre de Références Maladies Rares, Malformations Rares des Voies Urinaires (MARVU), Paris 97019, France
Matthieu Peycelon, Alaa El-Ghoneimi, Faculté de Médecine, Université de Paris, Paris 75006, France
Anca Tanase, Service d’Imagerie Pédiatrique, Hôpital Universitaire Robert-Debré, Assistance-Publique Hôpitaux de Paris, Paris 75019, France
Christine Grapin-Dagorno, Université Paris 13, Sorbonne Paris Cité, Paris 75013, France
Author contributions: Al-Shaqsi Y contributed to writing and editing; Peycelon M contributed to design and editing; Paye-Jaouen A, Carricaburu E, Tanase A, and Grapin-Dagorno C contributed to data collection and analyzing data; El-Ghoneimi A contributed to design and editing.
Institutional review board statement: This retrospective study was conducted in accordance with the ethical principles outlined in the Helsinki Declaration. Due to the nature of the study involving analysis of de-identified data from existing medical records, formal ethical approval from an institutional review board was not sought. However, efforts were made to ensure patient confidentiality and respect for individual privacy throughout the study process.
Informed consent statement: Informed consent was waived for this retrospective study as it involved the analysis of de-identified data obtained from existing medical records. The study was conducted in accordance with ethical principles and guidelines outlined in the Helsinki Declaration.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Yousuf Al-Shaqsi, MD, Doctor, Surgeon, Department of Pediatric Surgery, Sultan Qaboos University Hospital, Alkhoud BO BOX 38, Muscat 123, Oman. y.alshaqsi@hotmail.com
Received: November 20, 2023
Peer-review started: November 20, 2023
First decision: December 19, 2023
Revised: January 18, 2024
Accepted: March 12, 2024
Article in press: March 12, 2024
Published online: March 28, 2024
ARTICLE HIGHLIGHTS
Research background
Ureteropelvic obstruction is a common pediatric condition, which can be due to congenital internal obstruction or external obstruction secondary to crossing vessels. This study aims to encourage the use of dynamic contrast-enhanced magnetic resonance urography (dMRU) as a modality, measuring renal function as effectively as 99m-technetium mercaptoacetyltriglycine (MAG-3) and providing a good anatomical study in cases of obstruction due to crossing vessels.
Research motivation
dMRU proves advantageous as an alternative modality for ureteropelvic junction obstruction (UPJO). However, enhanced accessibility and cost-effectiveness can be achieved through advancements in magnetic resonance imaging technology.
Research objectives
The optimal imaging modalities for preoperative functional and anatomical assessment of UPJO in pediatric patients.
Research methods
Analysis of data in patients who underwent surgery for UPJO and had both dMRU and scintigraphy MAG-3 for split renal function assessment.
Research results
dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in UPJO cases of all pediatric age groups. Future implications emphasize the need for larger multicenter studies to confirm findings, while advancements in imaging technology hold promise for enhancing the accessibility and viability of dMRU as a gold standard diagnostic tool of UPJO.
Research conclusions
dMRU is an excellent alternative modality for the anatomical and functional evaluation of children with UPJO. A large sample size is required to confirm this hypothesis.
Research perspectives
To enhance the accessibility and viability of dMRU.
