Review
Copyright ©2012 Baishideng Publishing Group Co.
World J Cardiol. Oct 26, 2012; 4(10): 288-295
Published online Oct 26, 2012. doi: 10.4330/wjc.v4.i10.288
Figure 1
Figure 1 Basic principles of next generation sequencing. A whole genome or a targeted region of the genome are randomly digested into small fragments and then sequenced. The sequence obtained is subsequently aligned to a reference genome or de novo assembled.