Hydrogen alleviates right ventricular hypertrophy by inhibiting ferroptosis via restoration of the Nrf2/HO-1 signaling pathway

Figure 5 Hydrogen inhalation suppressed oxidative stress in monocrotaline-treated rats. A: Representative TEM images of mitochondrial morphology. The magnification is 10000 ×. Scale bar = 2 µm; B: Malonaldehyde content in right ventricular tissue; n = 6; C: Total superoxide dismutase activity in the serum; n = 10; D: Serum glutathione levels; n = 6; E: GSH-Px activity in the serum; n = 10. Data are expressed as the mean ± SD. ^bP < 0.05: MCT+H₂ group vs MCT group; ^cP < 0.01: MCT group vs control group. MCT: Monocrotaline; H₂: Hydrogen; MDA: Malonaldehyde; T-SOD: Total superoxide dismutase; GSH: Glutathione.