Hydrogen alleviates right ventricular hypertrophy by inhibiting ferroptosis via restoration of the Nrf2/HO-1 signaling pathway

Figure 2 Hydrogen inhalation alleviated cardiomyocyte area and fibrosis in monocrotaline-treated rats. A: Representative images of hematoxylin-eosin staining of heart tissue; n = 4; B: Representative images of Masson staining of heart tissue; n = 4; C: Representative images of wheat germ agglutinin staining of right ventricular tissue. Magnification is 20 ×. Scale bar = 50 µm; D: Analysis of the Masson staining of heart tissue; n = 4; E: Analysis of the cardiomyocyte area; n = 4. Data are expressed as the mean ± SD. ^bP < 0.05 MCT+H₂ group vs MCT group; ^cP < 0.01: MCT group vs control group. MCT: Monocrotaline; H₂: Hydrogen; WGA: Wheat germ agglutinin.