Mechanism of myocardial damage induced by doxorubicin via calumenin-regulated mitochondrial dynamics and the calcium–Cx43 pathway

Figure 7 Doxorubicin attenuated myocardial injury by inhibiting mitochondrial induced apoptosis. A: Protein levels of CHOP, cytochrome C, Bax and Bcl-2 were measured by western blotting; B: Protein levels of CHOP; C: Protein levels of cytochrome C; D: Protein levels of bax; E: Protein levels of Bcl-2. Data are expressed as mean ± SD, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs control group (n = 6) and (n = 3). CytC: Cytochrome C; DOX: Doxorubicin; CON: Control.