Patients’ time in therapeutic range on warfarin among atrial fibrillation patients in Warfarin Medication Therapy Adherence Clinic

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Cardiol. Sep 26, 2021; 13(9): 483-492
Published online Sep 26, 2021. doi: 10.4330/wjc.v13.i9.483

Table 1 Baseline characteristics

Baseline characteristic	*All patients, n =* 420**	*TTR < 60%, n =* 178**	*TTR ≥ 60%, n =* 242**
Age, yr
mean ± SD	65.7 ± 10.9	65.7 ± 10.8	65.7± 10.9
Median (IQR)	67 (15)	66 (14)	67 (15)
Male	227(54.0)	99 (55.6)	128 (52.9)
Female	193 (46.0)	79 (44.4)	114 (47.1)
Ethnicity
Malay	210 (50.0)	96 (53.9)	114 (47.1)
Chinese	179 (42.6)	64 (36.0)	115 (47.5)
Indian	26 (6.2)	16 (9.0)	10 (4.1)
Others	5 (1.2)	2 (1.1)	3 (1.2)
Comorbidities
Diabetes mellitus	170 (40.5)	85 (47.8)	85 (35.1)
Hypertension	291 (69.3)	128 (71.9)	163 (67.4)
Ischemic heart disease	90 (21.4)	48 (27.0)	42 (17.4)
Peripheral vascular disease	8 (1.9)	2 (1.1)	6 (2.5)
Stroke/transient ischemic attack	49 (11.7)	20 (11.2)	29 (12.0)
Deep vein thrombosis/pulmonary embolism	2 (0.5)	1 (0.6)	1 (0.4)
Heart failure	27 (6.4)	12 (6.7)	15 (6.2)
Chronic obstructive pulmonary disease/asthma	22 (5.2)	8 (4.5)	14 (5.8)
Chronic kidney disease	49 (11.7)	28 (15.7)	21 (8.7)
Dyslipidaemia	125 (29.8)	47 (26.4)	78 (32.2)
Chronic rheumatic heart disease	17 (4.0)	10 (5.6)	7 (2.9)
Liver disease	0 (0.0)	0 (0.0)	0 (0.0)
CHA₂DS₂-VASc score
Mean ± SD	2.6 ± 1.4	-	-
Median (IQR)	3 (1.0)	3 (2)	2(1)
Score 0-1	91 (21.7)	34 (19.1)	57 (23.6)
Score 2-4	297 (70.7)	125 (70.2)	172 (71.1)
Score ≥ 5	32 (7.6)	19 (10.7)	13 (5.4)
HAS-BLED score
Median (IQR)	2 (2.0)	3 (1.0)	2 (2.0)
Low bleeding risk (score ≤ 2)	257 (61.2)	83 (46.6)	174 (71.9)
High bleeding risk (score ≥ 3)	163 (38.8)	95 (53.4)	68 (28.1)

All values are reported as n (%) unless otherwise noted. IQR: Interquartile range; TTR: Time in therapeutic range; SD Standard deviation.

Citation: Lee SL, Ong TJ, Mazlan-Kepli W, Mageswaran A, Tan KH, Abd-Malek AM, Cronshaw R. Patients’ time in therapeutic range on warfarin among atrial fibrillation patients in Warfarin Medication Therapy Adherence Clinic. World J Cardiol 2021; 13(9): 483-492
URL: https://www.wjgnet.com/1949-8462/full/v13/i9/483.htm
DOI: https://dx.doi.org/10.4330/wjc.v13.i9.483

Lee SL, Ong TJ, Mazlan-Kepli W, Mageswaran A, Tan KH, Abd-Malek AM, Cronshaw R. Patients’ time in therapeutic range on warfarin among atrial fibrillation patients in Warfarin Medication Therapy Adherence Clinic. World J Cardiol 2021; 13(9): 483-492 [PMID: 34621493 DOI: 10.4330/wjc.v13.i9.483]

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