Prognostic value of left atrial size in hypertensive African Americans undergoing stress echocardiography

Table 2 Univariate predictors of all-cause mortality

Characteristic	Event	No event	Hazard ratio (95%CI)	P value
Clinical
Age	62.9	56.5	1.04 (1.02-1.06)	< 0.001
Male sex	40%	32%	1.43 (0.92-2.20]	0.109
Tobacco	79%	57%	2.55 (1.51-4.29)	< 0.001
Fam. History of CAD	28%	35%	0.73 (0.45-1.28)	0.194
Hyperlipidemia	48%	51%	0.91 (0.59-1.40)	0.662
Diabetes mellitus	52%	36%	1.77 (1.16-2.71)	0.008
Obesity	32%	47%	0.56 (0.35-0.88)	0.010
CAD	33%	17%	2.15 (1.37-3.38)	0.001
Heart failure	27%	9%	3.44 (2.13-5.56)	< 0.001
Atrial fibrillation	7%	2%	2.70 (1.18-6.19)	0.019
CKD (GFR < 60)	29%	15%	2.37 (1.48-3.78)	< 0.001
Systolic BP (mmHg)	141.5	140.0	1.01 (0.999-1.02)	0.438
Echocardiographic
Reduced EF	25%	9%	2.89 (1.76-4.72)	< 0.001
Abn. LA index (2.40 cut-point)	24%	7%	3.16 (1.91-5.22)	< 0.001
Abn. LA index (2.05 cut-point)	61%	28%	3.35 (2.17-5.18)	< 0.001
LV hypertrophy	52%	21%	3.62 (2.36-5.54)	< 0.001
Relative wall thickness	0.51	0.51	0.94 (0.19-4.57)	0.941
LV diastolic diameter	4.54	4.34	1.57 (1.15-2.13)	0.005
LV systolic diameter	3.24	2.98	1.54 (1.20-1.99)	0.001
Fractional shortening	0.30	0.32	0.05 (0.00-0.57)	0.017
IV septum thickness	1.20	1.11	2.51 (1.19-5.33)	0.016
LV post. wall thickness	1.13	1.07	2.48 (1.04-5.92)	0.040
Dobutamine study	68%	35%	3.55 (2.25-5.60)	< 0.001
Abnormal stress	35%	14%	2.76 (1.77-4.31)	< 0.001

CAD: Coronary artery disease; CKD: Chronic kidney disease; GFR: Glomerular filtration rate; BP: Blood pressure; EF: Ejection fraction; Abn. LA index: Abnormal left atrial diameter indexed to body surface area (cm/m²); LV: Left ventricular; IV: Intraventricular; Post.: Posterior; See text for further explanation of variables.