Satoh H, Sano M, Suwa K, Saitoh T, Nobuhara M, Saotome M, Urushida T, Katoh H, Hayashi H. Distribution of late gadolinium enhancement in various types of cardiomyopathies: Significance in differential diagnosis, clinical features and prognosis. World J Cardiol 2014; 6(7): 585-601 [PMID: 25068019 DOI: 10.4330/wjc.v6.i7.585]
Corresponding Author of This Article
Hiroshi Satoh, MD, PhD, Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ward, Hamamatsu 431-3192, Japan. satoh36@hama-med.ac.jp
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Topic Highlight
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World J Cardiol. Jul 26, 2014; 6(7): 585-601 Published online Jul 26, 2014. doi: 10.4330/wjc.v6.i7.585
Distribution of late gadolinium enhancement in various types of cardiomyopathies: Significance in differential diagnosis, clinical features and prognosis
Hiroshi Satoh, Makoto Sano, Kenichiro Suwa, Takeji Saitoh, Mamoru Nobuhara, Masao Saotome, Tsuyoshi Urushida, Hideki Katoh, Hideharu Hayashi, Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan
Author contributions: All authors contributed to this paper.
Correspondence to: Hiroshi Satoh, MD, PhD, Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ward, Hamamatsu 431-3192, Japan. satoh36@hama-med.ac.jp
Telephone: +81-53-4352267 Fax: +81-53-4342910
Received: December 20, 2013 Revised: March 21, 2014 Accepted: May 14, 2014 Published online: July 26, 2014
Core Tip
Core tip: We review characteristic cardiac magnetic resonance (CMR) features in ischemic and non-ischemic cardiomyopathies (NICM), especially in terms of location and distribution of late gadolinium enhancement (LGE). LGE in NICM does not correspond to any particular coronary artery distribution and is located mostly in the mid-wall to subepicardial layer. The analysis of LGE distribution is valuable to differentiate NICM with diffusely impaired systolic function; dilated cardiomyopathy, end-stage hypertrophic cardiomyopathy (HCM), cardiac sarcoidosis, and myocarditis, and those with diffuse LV hypertrophy; HCM, cardiac amyloidosis and Anderson-Fabry disease. The analyses of LGE distribution have potentials to predict cardiac outcomes and response to treatments.