Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Feb 26, 2024; 16(2): 58-63
Published online Feb 26, 2024. doi: 10.4330/wjc.v16.i2.58
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
Amedeo Tirandi, Elisa Schiavetta, Elia Maioli, Fabrizio Montecucco, Luca Liberale
Amedeo Tirandi, Elisa Schiavetta, Elia Maioli, Fabrizio Montecucco, Luca Liberale, Department of Internal Medicine, University of Genoa, Genoa 16132, Italy
Fabrizio Montecucco, Luca Liberale, IRCCS Ospedale Policlinico San Martino, Genoa – Italian Cardiovascular Network, Genoa 16132, Italy
Author contributions: Tirandi A wrote the paper and drew the image; Schiavetta E, and Maioli E critically revised the paper; Liberale L and Montecucco F supervised the entire work. All the authors read the final version of the manuscript and approve it for the submission and publication.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fabrizio Montecucco, MD, PhD, Full Professor, Department of Internal Medicine University of Genoa, 6 v.le Benedetto XV, Genoa 16132, Italy. fabrizio.montecucco@unige.it
Received: November 22, 2023
Peer-review started: November 22, 2023
First decision: December 23, 2023
Revised: January 1, 2024
Accepted: January 18, 2024
Article in press: January 18, 2024
Published online: February 26, 2024
Core Tip

Core Tip: Myeloproliferative neoplasms (MPNs) are a group of three diseases: essential thrombocythemia, polycythemia vera, and primary myelofibrosis. MPNs have a high risk of acute coronary syndromes due to a pro-thrombotic state. This state is induced by abnormal cancer cells that tend to proliferate and secrete several inflammatory cytokines, sustaining a pro-inflammatory state throughout the body. Clinically, MPN patients need to be carefully evaluated for cytoreductive treatments and cardiovascular protective strategies.