Vaina S, Milkas A, Crysohoou C, Stefanadis C. Coronary artery disease in women: From the yentl syndrome to contemporary treatment. World J Cardiol 2015; 7(1): 10-18 [PMID: 25632314 DOI: 10.4330/wjc.v7.i1.10]
Corresponding Author of This Article
Anastasios Milkas, MD, MSc, First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of Athens, Petropoulou 1 Melissia, 15127 Athens, Greece. tmhlkas@otenet.gr
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Cardiol. Jan 26, 2015; 7(1): 10-18 Published online Jan 26, 2015. doi: 10.4330/wjc.v7.i1.10
Coronary artery disease in women: From the yentl syndrome to contemporary treatment
Sofia Vaina, Anastasios Milkas, Christina Crysohoou, Christodoulos Stefanadis
Sofia Vaina, Anastasios Milkas, Christina Crysohoou, Christodoulos Stefanadis, First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of Athens, 15127 Athens, Greece
Author contributions: All authors have contributed equally to the development of this review.
Conflict-of-interest: All authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Anastasios Milkas, MD, MSc, First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of Athens, Petropoulou 1 Melissia, 15127 Athens, Greece. tmhlkas@otenet.gr
Telephone: +30-69-77224581 Fax: +30-21-07261585
Received: January 27, 2014 Peer-review started: January 30, 2014 First decision: March 19, 2014 Revised: November 16, 2014 Accepted: December 3, 2014 Article in press: January 4, 2015 Published online: January 26, 2015
Abstract
In recent years attention has been raised to the fact of increased morbidity and mortality between women who suffer from coronary disease. The identification of the so called Yentl Syndrome has emerged the deeper investigation of the true incidence of coronary disease in women and its outcomes. In this review an effort has been undertaken to understand the interaction of coronary disease and female gender after the implementation of newer therapeutic interventional and pharmaceutics’ approaches of the modern era.
Core tip: Coronary disease although remains a leading cause of morbidity and mortality in women, is however underestimated mainly because of the protective role of estrogens that results in lower rates of the disease until the age of mid-fifty. In this review detailed information about the prevalence and the consequences of the disease in women are quoted as well as evidence concerning the results of invasive treatment and use of modern drug therapy.
