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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2021; 13(2): 141-152
Published online Feb 27, 2021. doi: 10.4240/wjgs.v13.i2.141
Published online Feb 27, 2021. doi: 10.4240/wjgs.v13.i2.141
Hospital outcomes and early readmission for the most common gastrointestinal and liver diseases in the United States: Implications for healthcare delivery
Somashekar G Krishna, Alecia M Blaszczak, Gokulakrishnan Balasubramanian, Hisham Hussan, Peter P Stanich, Khalid Mumtaz, Darwin L Conwell, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Brandon K Chu, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Alice Hinton, Division of Biostatistics, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Author contributions: Krishna SG designed the study, interpreted the data, contributed to the figures and tables, revised the manuscript and supervised the study; Chu BK designed the study, interpreted the data, contributed to the figures and tables and wrote the manuscript; Blaszczak AM designed the study and wrote the manuscript; Conwell DL designed the study, interpreted the data and revised the manuscript. Hinton A performed the statistical analyses, designed the tables and revised the manuscript; Balasubramanian G, Hussan H, Stanich PP, and Mumtaz K interpreted the data and revised the manuscript.
Institutional review board statement: Data for this study was obtained from querying the Nationwide Readmission Database (2013) and the Nationwide Inpatient Sample (2012). Institutional Review Board approval was not necessary for a population-based public data set based on The Ohio State University Data and Specimen Policy and Human Subjects Research Policy.
Informed consent statement: Informed consent approval was not necessary for a population-based public data set based on The Ohio State University Data and Specimen Policy and Human Subjects Research Policy.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Data sharing statement: Data for this study was obtained from querying the Nationwide Readmission Database (2013) and the Nationwide Inpatient Sample (2012). No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Somashekar G Krishna, AGAF, FACG, FASGE, MD, Associate Professor, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, Suite 262, Columbus, OH 43210, United States. somashekar.krishna@osumc.edu
Received: November 12, 2020
Peer-review started: November 12, 2020
First decision: December 12, 2020
Revised: December 24, 2020
Accepted: January 14, 2021
Article in press: January 14, 2021
Published online: February 27, 2021
Peer-review started: November 12, 2020
First decision: December 12, 2020
Revised: December 24, 2020
Accepted: January 14, 2021
Article in press: January 14, 2021
Published online: February 27, 2021
Core Tip
Core Tip: Using the 2013 Nationwide Readmission Database, we sought to elucidate the hospital outcomes, including hospitalization costs, mortality rates, readmission rates, and factors contributing to readmission for the 13 most common gastrointestinal (GI)-related diseases. The results of our study highlight the large economic and healthcare burden for these 13 GI-related diseases and identify factors associated with early readmissions. Our study also reveals that preventable and non-chronic GI diseases such as Clostridium difficile, GI hemorrhage, and acute pancreatitis contribute a significant proportion of the overall costs, mortality, and readmission burden. Our data underscore a crucial opportunity for providers to aim at targeting preemptive care to reduce the initial and subsequent readmissions for these preventable GI-related diseases.