Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity

Figure 7 Effects on Visual Analogue Scale assessed appetite scores and ad libitum food intake in lean and obese subjects following physiological and supraphysiological[92-99] infusions of glucagon-like peptide 1. Though individual studies report conflicting data, a meta-analysis of clinical studies evaluating the acute effects of GLP-1 infusion on food intake reports a mean 11.7% decrease when compared with saline control[100]. GLP-1: Glucagon-like peptide 1.