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World J Diabetes. Feb 10, 2016; 7(3): 45-49
Published online Feb 10, 2016. doi: 10.4239/wjd.v7.i3.45
Role of diabetes in heart rhythm disorders
Buelent Koektuerk, Murat Aksoy, Marc Horlitz, Ilkay Bozdag-Turan, Ramazan Goekmen Turan
Buelent Koektuerk, Murat Aksoy, Marc Horlitz, Ramazan Goekmen Turan, Department of Cardiology/Electrophysiology, Witten/Herdecke University, Krankenhaus Porz am Rhein, 58448 Cologne, Germany
Ilkay Bozdag-Turan, Ramazan Goekmen Turan, Division of Cardiology, Department of Internal Medicine, University Hospital, 18055 Rostock, Germany
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ramazan Goekmen Turan, MD, PhD, Department of Cardiology/Electrophysiology, Witten/Herdecke University, Krankenhaus Porz am Rhein, Alfred-Herrhausen-Straße 50, 58448 Cologne, Germany. dr_g_turan@hotmail.com
Telephone: +49-2203-5666075 Fax: +49-2203-5661473
Received: September 29, 2015
Peer-review started: October 2, 2015
First decision: November 4, 2015
Revised: November 26, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: February 10, 2016
Processing time: 119 Days and 10 Hours
Abstract

The incidence of diabetes mellitus (DM) is increasing rapidly. DM is the leading cause of cardiovascular diseases, which can lead to varied cardiovascular complications by aggravated atherosclerosis in large arteries and coronary atherosclerosis, thereby grows the risk for macro and microangiopathy such as myocardial infarction, stroke, limb loss and retinopathy. Moreover diabetes is one of the strongest and independent risk factor for cardiovascular morbidity and mortality, which associated frequently rhythm disorders such as atrial fibrillation (AF) and ventricular arrhythmias (VA). The present article provides a concise overview of the association between DM and rhythm disorders such as AF and VA with underlying pathophysiological mechanisms.

Keywords: Atrial fibrillation; Diabetes mellitus; Cardiovascular complications; Pathophysiological mechanisms; Ventricular arrhythmias

Core tip: The incidence of diabetes mellitus (DM) is increasing rapidly. DM is the leading cause of cardiovascular diseases. Atrial fibrillation (AF) and ventricular arrhythmias (VA) are most common form of arrhythmias, which lead to cardiovascular complications and mortality in patients with DM. The present article provides a concise overview of the association between DM and rhythm disorders such as AF and VA with underlying pathophysiological mechanisms.