Esophageal granular cell tumors: Case report and literature review

Table 1 Clinicopathological data of five cases of granular cell tumor

Case	Gender	Age (yr)	Esophageal location	Diameter (cm)	Color and quality	Surface
1	Female	43	Middle	0.5	Gray–white	Smooth
2	Female	32	Middle	0.4	Gray–white	Smooth
3	Male	47	Distal	2.5	Gray–white and pink, fine quality	Erosion
4	Female	42	Upper	0.6	Grayish yellow (Figure 1)	Smooth
5	Female	56	Distal	0.8	Yellow	Slightly concave

Table 2 Immunohistochemical and histochemical staining of five cases of granular cell tumor

Case	S-100	NSE	Vim	CD68	Des	SMA	CK	Ki-67	CD117	CD34a	EMA	PAS	Dog-1
1	+	+	+	+	-	-	-	-	Noneb	None	None	Weak+	None
2	+	+	+	+	None	-	-	-	-	-	Weak+	Weak+	None
3	+	+	+	+	-	-	-	2%+	-	-	None	Weak+	-
4	+	+	+	+	None	None	-	None	None	None	Weak+	Weak+	None
5	+	+	+	+	None	-	-	5%+	-	-	None	Weak+	-

^aSurrounding mesenchymal cells were positive for CD34;

^bNone means the tissue was too small, and immunohistochemical staining was not possible. CK: Cytokeratin; Des: Desmin; EMA: Epithelial membrane antigen; Vim: Vimentin; NSE: Neuron speoific enolase; SMA: Smooth muscle actin; PAS: Periodic acid-Schiff.