Role of histone deacetylases in pancreas: Implications for pathogenesis and therapy

doi:10.4251/wjgo.v7.i12.473

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2015; 7(12): 473-483
Published online Dec 15, 2015. doi: 10.4251/wjgo.v7.i12.473

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Figure 4 Role of histone deacetylase 6 in protein turnover. HDAC6 facilitates un-/misfolded protein degradation by recruiting ubiquinated proteins to the aggresome or proteasome thus protecting tumor cells from apoptosis - see text for details[58]. HDAC6: Histone deacetylase 6.

Citation: Klieser E, Swierczynski S, Mayr C, Schmidt J, Neureiter D, Kiesslich T, Illig R. Role of histone deacetylases in pancreas: Implications for pathogenesis and therapy. World J Gastrointest Oncol 2015; 7(12): 473-483
URL: https://www.wjgnet.com/1948-5204/full/v7/i12/473.htm
DOI: https://dx.doi.org/10.4251/wjgo.v7.i12.473