Nuclear localization of proteasome subunit beta 5 serves as an independent prognostic biomarker and promotes invasion in colorectal cancer

doi:10.4251/wjgo.122057

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Aug 15, 2026; 18(8): 122057
Published online Aug 15, 2026. doi: 10.4251/wjgo.122057

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Figure 6 Impact of proteasome subunit beta 5 knockdown on colorectal cancer cell migration assessed by scratch assay. A and B: Representative scratch assay images of SW620 and SW480 cells following proteasome subunit beta 5 silencing; C and D: Quantification of wound closure for SW620 and SW480 cells transfected with a proteasome subunit beta 5 small interfering RNA pool vs non-targeting control mall interfering RNA. Data are presented as mean ± SD; ^aP < 0.001 vs non-targeting control small interfering RNA group. Scr: Non-targeting control small interfering RNA; sipool: Proteasome subunit beta 5-targeting small interfering RNA pool.

Citation: Xu AP, She SP, Xiao YS, Lang J, Yuan JF, Zeng YF. Nuclear localization of proteasome subunit beta 5 serves as an independent prognostic biomarker and promotes invasion in colorectal cancer. World J Gastrointest Oncol 2026; 18(8): 122057
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/122057.htm
DOI: https://dx.doi.org/10.4251/wjgo.122057

Xu AP, She SP, Xiao YS, Lang J, Yuan JF, Zeng YF. Nuclear localization of proteasome subunit beta 5 serves as an independent prognostic biomarker and promotes invasion in colorectal cancer. World J Gastrointest Oncol 2026; 18(8): 122057 [DOI: 10.4251/wjgo.122057]

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