Nuclear localization of proteasome subunit beta 5 serves as an independent prognostic biomarker and promotes invasion in colorectal cancer

Figure 5 Effect of proteasome subunit beta 5 knockdown on the invasion of colorectal cancer cells assessed by Transwell assay. A: Representative images of invading SW620 and SW480 cells, respectively, after proteasome subunit beta 5 knockdown; B: Quantitative analysis of invasion for SW480 and SW620 cells transfected with a proteasome subunit beta 5 small interfering RNA pool or non-targeting control mall interfering RNA. Data are presented as mean ± SD; ^aP < 0.05, ^bP < 0.01 vs non-targeting control small interfering RNA group. Scr: Non-targeting control small interfering RNA; sipool: Proteasome subunit beta 5-targeting small interfering RNA pool.