Risk prediction of acute variceal bleeding in hepatocellular carcinoma patients undergoing systemic therapy based on immune checkpoint inhibitors

Figure 4 Calibration curve analysis of the model prediction for acute variceal bleeding. A: Training cohort; B: Validation cohort. Internal validation with 1000 bootstrap replicates showed good model fit (Hosmer-Lemeshow P = 0.067) and discrimination (C-statistic 0.861). External validation maintained calibration stability (P = 0.161), indicating excellent calibration performance and readiness for clinical implementation.