Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis

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Aug 15, 2025 (publication date) through Aug 26, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Aug 15, 2025; 17(8): 108870
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.108870

Table 1 Comparison of pre-chemotherapy serum S100A12 and soluble CD14 Levels between colorectal cancer patients and healthy controls

Group	S100A12 (ng/mL)	Soluble CD14 (ng/mL)
Colorectal cancer patients (n = 104)	158.64 ± 21.37	3345.29 ± 412.84
Healthy controls (n = 104)	89.72 ± 18.95	2384.61 ± 376.21
t value	78.611	17.540
P value	< 0.001	< 0.001

Citation: Ling MZ, Wan Z, Hu B, Zhao MJ, Gong HS, Li G. Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis. World J Gastrointest Oncol 2025; 17(8): 108870
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/108870.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.108870