Tumor markers and multimodal magnetic resonance imaging in predicting rectal cancer stage and differentiation

Table 8 Diagnostic value of tumor markers combined with magnetic resonance imaging in differentiation degree of rectal cancer patients

Indicator	AUC	95%CI	P value	Sensitivity (%)	Specificity (%)
AFP	0.815	0.721-0.896	< 0.001	75.4	76.2
CA19-9	0.887	0.817-0.955	< 0.001	89.2	91.2
CEA	0.894	0.842-0.964	< 0.001	90.5	88.1
CA72-4	0.916	0.866-0.975	< 0.001	89.6	89.4
MRI	0.923	0.873-0.975	< 0.001	91.3	93.1
Combined detection	0.978	0.946-0.998	< 0.001	93.6	97.1

AUC: Area under the curve; CI: Confidence interval; AFP: Alpha-fetoprotein; MRI: Magnetic resonance imaging; CA72-4: Cancer antigen 72-4; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen.