Tumor markers and multimodal magnetic resonance imaging in predicting rectal cancer stage and differentiation

Table 7 Diagnostic value of tumor markers combined with magnetic resonance imaging in preoperative T stage of rectal cancer

Indicator	AUC	95%CI	P value	Sensitivity (%)	Specificity (%)
AFP	0.669	0.604-0.735	< 0.001	73.5	76.7
MRI	0.771	0.709-0.833	< 0.001	83.1	85.8
CA72-4	0.789	0.741-0.836	< 0.001	65.2	78.6
CA19-9	0.846	0.802-0.889	< 0.001	89.5	82.6
CEA	0.879	0.838-0.921	< 0.001	85.3	91.2
Combined detection	0.947	0.899-0.994	< 0.001	93.7	94.6

AUC: Area under the curve; CI: Confidence interval; AFP: Alpha-fetoprotein; MRI: Magnetic resonance imaging; CA72-4: Cancer antigen 72-4; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen.